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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Fbln5
fibulin 5
MGI:1346091
24 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Fbln5tm1.1Hiya/Fbln5tm1.1Hiya
involves: 129S6/SvEvTac 		decreased angiogenesis J:159246
decreased tumor growth/size J:159246
Fbln5tm1Eno/Fbln5tm1Eno
involves: 129S6/SvEvTac 		abnormal aorta elastic fiber morphology J:86754
abnormal aorta morphology J:86754
abnormal aortic arch and aortic arch branch attachment J:86754
abnormal ascending aorta morphology J:86754
abnormal lung morphology J:86754
abnormal pulmonary alveolus morphology J:86754
abnormal pulmonary circulation J:86754
abnormal systemic arterial blood pressure J:86754
abnormal terminal bronchiole morphology J:86754
emphysema J:86754
loose skin J:86754
rough coat J:86754
Fbln5tm1Eno/Fbln5tm1Eno
involves: 129S6/SvEvTac * C57BL/6 		abnormal blood vessel elastic tissue morphology J:96831
abnormal blood vessel physiology J:96831
abnormal vascular smooth muscle physiology J:96831
abnormal vascular wound healing J:96831
decreased angiogenesis J:159246
decreased metastatic potential J:159246
decreased tumor growth/size J:159246
increased susceptibility to induced thrombosis J:96831
oxidative stress J:159246
Fbln5tm1Krc/Fbln5tm1Krc
involves: 129X1/SvJ * C57BL/6 		abnormal aorta morphology J:86753
abnormal craniofacial morphology J:86753
abnormal lung morphology J:86753
abnormal pulmonary alveolus morphology J:86753
abnormal pulmonary circulation J:86753
abnormal terminal bronchiole morphology J:86753
dilated heart right ventricle J:86753
emphysema J:86753
loose skin J:86753
short snout J:86753
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory