Adamts5 Phenotype Annotations

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Adamts5
ADAM metallopeptidase with thrombospondin type 1 motif 5
MGI:1346321

9 phenotypes from 6 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Adamts5^tm1.1Eam/Adamts5⁺ involves: 129S5/SvEvBrd	decreased susceptibility to induced arthritis	J:97590
Adamts5^tm1.1Eam/Adamts5^tm1.1Eam involves: 129S5/SvEvBrd	decreased susceptibility to induced arthritis	J:97590
Adamts5^tm1.1Lex/Adamts5^tm1.1Lex involves: 129S/SvEvBrd	normal skeleton phenotype	J:120892
Adamts5^tm1Dgen/Adamts5^tm1Dgen B6.129P2-Adamts5^tm1Dgen/J	interdigital webbing	J:155754
Adamts5^tm1Dgen/Adamts5^tm1Dgen B6.129P2-Adamts5^tm1Dgen/J	syndactyly	J:155754
Adamts5^tm1Eam/Adamts5⁺ involves: 129S5/SvEvBrd	no abnormal phenotype detected	J:97590
Adamts5^tm1Lex/Adamts5^tm1.1Lex Tg(CMV-cre)1Cgn/? involves: 129S5/SvEvBrd * BALB/cJ	abnormal cartilage morphology	J:105138
	normal reproductive system phenotype	J:105138
Adamts5^tm1Lex/Adamts5^tm1Lex Tg(CMV-cre)1Cgn/0 involves: 129S5/SvEvBrd * BALB/cJ	osteoarthritis	J:105138
Adamts5^tm2.2Lex/Adamts5^tm2.2Lex B6.129S5-Adamts5^tm2.2Lex	abnormal pain threshold	J:175366
Adamts5^tm2.2Lex/Adamts5^tm2.2Lex B6.129S5-Adamts5^tm2.2Lex	decreased susceptibility to induced arthritis	J:175366

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24