Fyb1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fyb1
FYN binding protein 1
MGI:1346327

10 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fyb1^{tm1b(EUCOMM)Hmgu}/Fyb1^{tm1b(EUCOMM)Hmgu} C57BL/6N-Fyb1^{tm1b(EUCOMM)Hmgu}/Cnrm	abnormal lens morphology	J:211773
	cataract	J:211773
	increased respiratory quotient	J:211773
	thrombocytopenia	J:211773
Fyb1^tm1Gak/Fyb1^tm1Gak B6.129-Fyb1^tm1Gak	normal immune system phenotype	J:112087
Fyb1^tm1Gak/Fyb1^tm1Gak involves: 129S1/Sv * 129X1/SvJ	abnormal leukocyte adhesion	J:111368
	abnormal T cell physiology	J:126545
	decreased interleukin-2 secretion	J:111368, J:126545
	decreased T cell proliferation	J:111368, J:126545
	decreased thymocyte number	J:111368
	thrombocytopenia	J:111368

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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