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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Taf7
TATA-box binding protein associated factor 7
MGI:1346348
13 phenotypes from 2 alleles in 1 genetic background
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Allelic Composition
Genetic Background		 Annotated Term Reference
Taf7tm1.1Dss/Taf7tm1.1Dss
involves: C57BL/6 		abnormal embryo development J:185745
embryonic lethality, complete penetrance J:185745
Taf7tm1.1Dss/Taf7tm1.2Dss
Tg(Cd8a*-cre)B8Asin/0
involves: C57BL/6 		abnormal T cell differentiation J:185745
decreased CD4-positive, alpha-beta T cell number J:185745
decreased CD8-positive, alpha-beta T cell number J:185745
decreased double-positive T cell number J:185745
decreased single-positive T cell number J:185745
decreased T cell number J:185745
decreased T cell proliferation J:185745
decreased thymocyte number J:185745
Taf7tm1.1Dss/Taf7tm1.2Dss
Tg(Lck-cre)1Cwi/0
involves: C57BL/6 		abnormal T cell differentiation J:185745
abnormal thymus physiology J:185745
decreased CD4-positive, alpha-beta T cell number J:185745
decreased CD8-positive, alpha-beta T cell number J:185745
decreased double-positive T cell number J:185745
decreased thymocyte number J:185745
increased double-negative T cell number J:185745
small thymus J:185745
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory