Sgcb Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sgcb
sarcoglycan, beta (dystrophin-associated glycoprotein)
MGI:1346523

22 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sgcb^em1Isrd/Sgcb^em1Isrd involves: 129 * C57BL/6N	no abnormal phenotype detected	J:257027
Sgcb^tm1Kcam/Sgcb^tm1Kcam involves: 129S1/Sv * 129X1/SvJ	abnormal blood vessel morphology	J:60154
	abnormal muscle morphology	J:60154
	abnormal sarcolemma morphology	J:60154
	abnormal vascular smooth muscle morphology	J:60154
	aneurysm	J:60154
	calcified muscle	J:60154
	cardiac fibrosis	J:60154
	cardiomyopathy	J:60154
	dystrophic muscle	J:60154
	muscular atrophy	J:60154
	myocardium necrosis	J:60154
	vascular stenosis	J:60154
Sgcb^tm1Oza/Sgcb^tm1Oza involves: 129S4/SvJae * C57BL/6J	abnormal skeletal muscle morphology	J:57590
	cardiac fibrosis	J:57590
	centrally nucleated skeletal muscle fibers	J:57590
	dystrophic muscle	J:57590
	increased body size	J:57590
	increased body weight	J:57590
	increased gastrocnemius weight	J:57590
	increased tibialis anterior weight	J:57590
	myositis	J:57590
	skeletal muscle fiber degeneration	J:57590
	skeletal muscle fiber necrosis	J:57590

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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