About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Sgcd
sarcoglycan, delta (dystrophin-associated glycoprotein)
MGI:1346525
30 phenotypes from 3 alleles in 4 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Sgcdtm1Kcam/Sgcdtm1Kcam
involves: 129S1/Sv * 129X1/SvJ 		abnormal cardiovascular system physiology J:57107
abnormal heart morphology J:57107
cardiac fibrosis J:57107
cardiomyopathy J:57107
coronary artery stenosis J:57107
decreased QRS amplitude J:57107
dilated cardiomyopathy J:57107
dilated heart ventricle J:57107
dystrophic cardiac calcinosis J:57107
dystrophic muscle J:57107
increased susceptibility to induced morbidity/mortality J:57107
myocardium necrosis J:57107
premature death J:57107
skeletal muscle necrosis J:57107
Sgcdtm1Mcn/Sgcdtm1Mcn
B6.129-Sgcdtm1Mcn/J 		abnormal muscle physiology J:250485
abnormal skeletal muscle morphology J:250485
cardiac fibrosis J:234761, J:250485
cardiac muscle degeneration J:234761
cardiac muscle necrosis J:234761
decreased cardiac muscle contractility J:234761
decreased grip strength J:250485
decreased pulmonary respiratory rate J:250485
dilated cardiomyopathy J:234761
dystrophic muscle J:250485
increased circulating creatine kinase level J:250485
skeletal muscle fibrosis J:250485
Sgcdtm1Mcn/Sgcdtm1Mcn
involves: 129S1/Sv * 129T2/SvEmsJ * 129X1/SvJ 		abnormal muscle contractility J:76730
abnormal muscle physiology J:76730
cardiomyopathy J:76730
dystrophic muscle J:76730
increased circulating creatine kinase level J:76730
muscle degeneration J:76730
perivascular fibrosis J:76730
premature death J:76730
Sgcdtm1Ojml/Sgcd+
B6.129-Sgcdtm1Ojml 		abnormal response to exercise J:234761
decreased aerobic running capacity J:234761
dilated cardiomyopathy J:234761
increased heart weight J:234761
Sgcdtm1Ojml/Sgcdtm1Ojml
B6.129-Sgcdtm1Ojml 		prenatal lethality, complete penetrance J:234761
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory