Psmb8 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Psmb8
proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)
MGI:1346527

4 phenotypes from 1 allele in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Psmb8^tm1Hjf/Psmb8^tm1Hjf either: 129P2/OlaHsd or (involves: 129P2/OlaHsd * C57BL/6)	decreased level of surface class I molecules	J:20012
	defective intracellular transport of class I molecules	J:20012
Psmb8^tm1Hjf/Psmb8^tm1Hjf involves: 129P2/OlaHsd	abnormal dendritic cell antigen presentation	J:180765
Psmb8^tm1Hjf/Psmb8^tm1Hjf involves: 129P2/OlaHsd	decreased level of surface class I molecules	J:180765
Psmb8^tm1Hjf/Psmb8^tm1Hjf involves: 129P2/OlaHsd * C57BL/6	abnormal tumor susceptibility	J:108550

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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