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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Esrrb
estrogen related receptor, beta
MGI:1346832
37 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Esrrbtm1.1Nat/Esrrbtm1.1Nat
Tg(Myh6-cre)2182Mds/0
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6N * FVB/N 		abnormal myocardial fiber physiology J:241078
abnormal sarcomere morphology J:241078
cardiac fibrosis J:241078
congestive heart failure J:241078
decreased calcium uptake by cardiac muscle J:241078
decreased cardiac muscle contractility J:241078
decreased heart ventricle muscle contractility J:241078
dilated cardiomyopathy J:241078
dilated heart left ventricle J:241078
enlarged heart J:241078
increased calcium uptake by cardiac muscle J:241078
premature death J:241078
Esrrbtm1.1Nat/Esrrbtm1.2Nat
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S6/SvEvTac * C57BL/6 * CBA * SJL 		abnormal scala media morphology J:124941
abnormal semicircular canal ampulla morphology J:124941
abnormal semicircular canal morphology J:124941
absent startle reflex J:124941
circling J:124941
decreased endolymph production J:124941
head bobbing J:124941
increased or absent threshold for auditory brainstem response J:124941
small scala media J:124941
Esrrbtm1.1Nat/Esrrbtm1.2Nat
Tg(Nes-cre)1Kln/0
involves: 129S6/SvEvTac * C57BL/6 * SJL 		absent strial marginal cells J:124941
increased or absent threshold for auditory brainstem response J:124941
Esrrbtm1.2Nat/Esrrbtm1.2Nat
involves: 129S6/SvEvTac * C57BL/6 * CBA * SJL 		prenatal lethality, complete penetrance J:124941
Esrrbtm1Vgi/Esrrbtm1Vgi
involves: 129S1/Sv * 129X1/SvJ 		abnormal chorion morphology J:42488
abnormal extraembryonic tissue morphology J:42488
abnormal placenta morphology J:42488
abnormal trophoblast giant cell morphology J:42488
abnormal trophoblast layer morphology J:42488
absent chorion J:42488
absent placental labyrinth J:42488
absent spongiotrophoblast J:42488
decreased embryo size J:42488
decreased trophoblast giant cell number J:42488
disorganized embryonic tissue J:42488
embryonic growth retardation J:42488
embryonic lethality during organogenesis, complete penetrance J:42488
failure of chorioallantoic fusion J:42488
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory