Nr5a2 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nr5a2
nuclear receptor subfamily 5, group A, member 2
MGI:1346834

10 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Ldlr^tm1Her/Ldlr^tm1Her Nr5a2^tm1Sjns/Nr5a2^tm1Sjns Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ involves: 129/Sv * 129S7/SvEvBrd * C57BL/6 * C57BL/6J * DBA	abnormal feces lipid level	J:215556
	abnormal sterol level	J:215556
	normal cardiovascular system phenotype	J:215556
Ldlr^tm1Her/Ldlr^tm1Her Nr5a2^tm3.1Sjns/Nr5a2^tm3.1Sjns involves: 129S7/SvEvBrd * C57BL/6J * C57BL/6N	abnormal bile secretion	J:215556
	abnormal cholesterol homeostasis	J:215556
	decreased cholesterol level	J:215556
	decreased circulating LDL cholesterol level	J:215556
	decreased circulating triglyceride level	J:215556
	decreased susceptibility to atherosclerosis	J:215556
	increased liver cholesterol level	J:215556

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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