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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Mapk3
mitogen-activated protein kinase 3
MGI:1346859
18 phenotypes from 3 alleles in 8 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Mapk3m1Btlr/Mapk3m1Btlr
C57BL/6J-Mapk3m1Btlr 		decreased interleukin-1 beta secretion J:221481
Mapk3tm1Gela/Mapk3tm1Gela
129(Cg)-Mapk3tm1Gela 		increased locomotor activity J:77455
normal nervous system phenotype J:89787
Mapk3tm1Gela/Mapk3tm1Gela
either: 129(Cg)-Mapk3tm1Gela or B6.129-Mapk3tm1Gela 		abnormal cytokine secretion J:107504
increased susceptibility to experimental autoimmune encephalomyelitis J:107504
Mapk3tm1Gela/Mapk3tm1Gela
involves: 129S1/Sv * 129X1/SvJ 		normal embryo phenotype J:144862
normal mortality/aging J:144862
Mapk3tm1Gela/Mapk3tm1Gela
involves: 129S1/SvImJ 		normal nervous system phenotype J:137882
Mapk3tm1Gpg/Mapk3tm1Gpg
involves: 129 		cardiac hypertrophy J:124903
decreased T cell number J:58468
decreased T cell proliferation J:58468
premature death J:124903
Mapk3tm1Gpg/Mapk3tm1Gpg
involves: 129/Sv * C57BL/6 		abnormal active avoidance behavior J:89788
abnormal passive avoidance behavior J:89788
normal cellular phenotype J:162580
increased locomotor activity J:89788
normal muscle phenotype J:190460
reduced long-term potentiation J:89788
Mapk3tm1Gpg/Mapk3tm1Gpg
involves: 129/Sv * C57BL/6 * CD-1 		decreased fibroblast proliferation J:162580
normal growth/size/body region phenotype J:162580
normal mortality/aging J:162580
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory