Mapk9 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mapk9
mitogen-activated protein kinase 9
MGI:1346862

22 phenotypes from 2 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mapk9^tm1Flv/Mapk9^tm1Flv B6.129S2-Mapk9^tm1Flv	abnormal keratinocyte morphology	J:93433
	epidermal hyperplasia	J:93433
	increased keratohyalin granule number	J:93433
	thick epidermis	J:93433
Mapk9^tm1Flv/Mapk9^tm1Flv B6.129S2-Mapk9^tm1Flv/J	abnormal liver physiology	J:113452
	decreased susceptibility to induced morbidity/mortality	J:113452
	decreased susceptibility to injury	J:113452
Mapk9^tm1Flv/Mapk9^tm1Flv involves: 129P2/OlaHsd * C57BL/6	abnormal enzyme/coenzyme activity	J:112737
Mapk9^tm1Flv/Mapk9^tm1Flv involves: 129S2/SvPas	abnormal T-helper 1 cell differentiation	J:50628
Mapk9^tm1Flv/Mapk9^tm1Flv involves: 129S2/SvPas	normal cardiovascular system phenotype	J:108253
Mapk9^tm1Mka/Mapk9^tm1Mka B6.129-Mapk9^tm1Mka	abnormal physiological response to xenobiotic	J:103476
Mapk9^tm1Mka/Mapk9^tm1Mka B6.129-Mapk9^tm1Mka	normal homeostasis/metabolism phenotype	J:80452
Mapk9^tm1Mka/Mapk9^tm1Mka either: (involves: 129S2/SvPas * C57BL/6) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)	abnormal excitatory postsynaptic potential	J:105153
	abnormal neurotransmitter secretion	J:105153
	decreased paired-pulse facilitation	J:105153
	decreased post-tetanic potentiation	J:105153
	reduced long-term potentiation	J:105153
Mapk9^tm1Mka/Mapk9^tm1Mka either: (involves: 129S2/SvPas) or (involves: 129S1/Sv * 129X1/SvJ)	abnormal T cell activation	J:78129
	decreased T cell apoptosis	J:78129
	decreased T cell proliferation	J:78129
Mapk9^tm1Mka/Mapk9^tm1Mka involves: 129/Sv * C57BL/6	abnormal myocardium layer morphology	J:102152
Mapk9^tm1Mka/Mapk9^tm1Mka involves: 129/Sv * C57BL/6	decreased cardiomyocyte apoptosis	J:102152

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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