Map2k7 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Map2k7
mitogen-activated protein kinase kinase 7
MGI:1346871

12 phenotypes from 8 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Map2k7^tm1.1Twad/Map2k7^tm1.1Twad B6.Cg-Map2k7^tm1.1Twad	no abnormal phenotype detected	J:170904
Map2k7^tm1.1Twad/Map2k7^tm1.1Twad Tg(KRT5-cre)1Tak/0 involves: 129P2/OlaHsd * C3H * C57BL/6	eyelids open at birth	J:170904
Map2k7^tm1.1Twad/Map2k7^tm1.2Twad Tg(MMTV-cre)4Mam/0 involves: 129P2/OlaHsd * C57BL/6 * FVB	normal reproductive system phenotype	J:170904
Map2k7^{tm1a(EUCOMM)Wtsi}/Map2k7^{tm1a(EUCOMM)Wtsi} C57BL/6N-Map2k7^{tm1a(EUCOMM)Wtsi}/Wtsi	preweaning lethality, complete penetrance	J:211773
Map2k7^tm1Flv/Map2k7^tm1Flv involves: 129S1/Sv	embryonic lethality, complete penetrance	J:61895
Map2k7^tm1Pngr/Map2k7⁺ involves: 129P2/OlaHsd * C57BL/6J	abnormal spatial working memory	J:188339
Map2k7^tm1Rjd/Map2k7^tm1Rjd Tg(CAG-cre/Esr1)5Amc/0 involves: C57BL/6 CBA	normal nervous system phenotype	J:178060
Map2k7^tm2.1Rjd/Map2k7^tm2.1Rjd B6.129S6-Map2k7^tm2.1Rjd	embryonic lethality, complete penetrance	J:101977
Tg(Myh6-Map2k7)1Jmol/0 involves: FVB/N	abnormal cardiac muscle contractility	J:102152
	cardiac hypertrophy	J:102152
	decreased cardiomyocyte apoptosis	J:102152
	decreased myocardial infarct size	J:102152
	increased heart weight	J:102152

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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