Map3k4 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Map3k4
mitogen-activated protein kinase kinase kinase 4
MGI:1346875

12 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Del(17)T^hp/Map3k4^byg involves: AKR/J * C3H/HeH * C57BL/6J	abnormal neural tube morphology	J:153050
	abnormal testis cord formation	J:153050
	primary sex reversal	J:153050
Del(17)T^hp/Map3k4^C57BL/6J involves: AKR/J * C57BL/6J	abnormal primary sex determination	J:7073
	abnormal secondary sex determination	J:7073
	ovotestis	J:7073
	primary sex reversal	J:7073
	reduced fertility	J:7073
	sex reversal	J:7073
	true hermaphroditism	J:7073
Gadd45g^tm1Jni/Gadd45g⁺ Map3k4^tm1Flv/Map3k4⁺ involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J	abnormal testis development	J:191096
Gadd45g^tm1Jni/Gadd45g⁺ X/Sry^AKR/J Tg(Map3k4)#Agre/0 involves: 129P2/OlaHsd * AKR/J * C57BL/6J	normal reproductive system phenotype	J:191096
Map3k4^tm1Flv/Map3k4⁺ X/Sry^AKR/J B6.Cg-Map3k4^tm1Flv Chr Y^AKR	ovotestis	J:153050
	primary sex reversal	J:153050
	small testis	J:153050

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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