Dapp1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dapp1
dual adaptor for phosphotyrosine and 3-phosphoinositides 1
MGI:1347063

7 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dapp1^{Gt(OST111213)Lex}/Dapp1^{Gt(OST111213)Lex} B6.Cg-Dapp1^{Gt(OST111213)Lex}	abnormal humoral immune response	J:110009
	decreased B cell proliferation	J:110009
	decreased IgG3 level	J:110009
	increased susceptibility to bacterial infection	J:110009
Dapp1^tm1Mnz/Dapp1^tm1Mnz B6.129P2-Dapp1^tm1Mnz	abnormal B cell activation	J:86182
	decreased B cell proliferation	J:86182
	decreased B-1a cell number	J:86182
	decreased IgG3 level	J:86182
	decreased IgM level	J:86182

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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