Fto Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fto
FTO alpha-ketoglutarate dependent dioxygenase
MGI:1347093

13 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Fto^tm1Urt/Fto^tm1Urt Lep^ob/Lep^ob involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal adipose tissue morphology	J:219118
	decreased body length	J:219118
	decreased locomotor activity	J:219118
	enlarged pancreatic islets	J:219118
	hepatic steatosis	J:219118
	increased body weight	J:219118
	increased fat cell size	J:219118
	increased gonadal fat pad weight	J:219118
	increased inguinal fat pad weight	J:219118
	increased interscapular fat pad weight	J:219118
	increased liver weight	J:219118
	increased percent body fat/body weight	J:219118
	insulin resistance	J:219118

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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