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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Slc7a11
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
MGI:1347355
15 phenotypes from 4 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Slc7a11m1Mtka/Slc7a11m1Mtka
C57BL/6-Slc7a11m1Mtka 		abnormal dendritic cell physiology J:159323
abnormal macrophage physiology J:159323
decreased fibroblast proliferation J:159323
normal immune system phenotype J:159323
increased incidence of tumors by chemical induction J:159323
Slc7a11sut/Slc7a11sut
C3H/HeSnJ-Slc7a11sut/J 		decreased platelet serotonin level J:31616
diluted coat color J:14274
increased bleeding time J:31616
Slc7a11tm1b(EUCOMM)Wtsi/Slc7a11tm1b(EUCOMM)Wtsi
C57BL/6N-Slc7a11tm1b(EUCOMM)Wtsi/Ics 		abnormal auditory brainstem response J:211773
abnormal optic disk morphology J:211773
abnormal vitreous body morphology J:211773
increased circulating glucose level J:211773
Slc7a11tm1Hsat/Slc7a11tm1Hsat
involves: 129P2/OlaHsd * C57BL/6 		abnormal cell death J:102902
abnormal circulating amino acid level J:102902
decreased fibroblast proliferation J:102902
increased circulating cysteine level J:102902
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory