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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Adamts2
ADAM metallopeptidase with thrombospondin type 1 motif 2
MGI:1347356
24 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Adamts14Gt(511E11)Cmhd/Adamts14Gt(511E11)Cmhd
Adamts2tm1Prc/Adamts2tm1Prc
involves: 129 * 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal cutaneous collagen fibril morphology J:271185
abnormal homeostasis J:271185
abnormal T cell activation J:271185
abnormal tendon collagen fibril morphology J:271185
cutaneous mastocytosis J:271185
decreased B cell number J:271185
decreased CD8-positive, alpha-beta T cell number J:271185
decreased skin tensile strength J:271185
dermal hyperplasia J:271185
dermatitis J:271185
normal homeostasis/metabolism phenotype J:271185
increased CD4-positive, alpha-beta T cell number J:271185
increased interferon-gamma secretion J:271185
increased interleukin-2 secretion J:271185
increased keratinocyte apoptosis J:271185
increased keratinocyte proliferation J:271185
increased T cell proliferation J:271185
normal integument phenotype J:271185
male infertility J:271185
mixed cellular infiltration to dermis J:271185
ruffled hair J:271185
spontaneous skin ulceration J:271185
thick epidermis J:271185
normal vision/eye phenotype J:271185
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory