About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Foxc1
forkhead box C1
MGI:1347466
64 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Foxc1tm1Blh/Foxc1+
Tyrc-2J/Tyrc-2J
B6.Cg-Tyrc-2J Foxc1tm1Blh 		abnormal aqueous drainage system morphology J:82280
abnormal trabecular meshwork morphology J:82280
absent Schlemm's canal J:82280
iris synechia J:82280
Foxc1tm1Blh/Foxc1+
Foxc2tm1Blh/Foxc2+
involves: 129S6/SvEvTac * Black Swiss 		abnormal aortic valve morphology J:57677
abnormal branching involved in ureteric bud morphogenesis J:60834
abnormal canal of Schlemm morphology J:61775
abnormal ciliary body morphology J:61775
abnormal cornea morphology J:61775
abnormal fourth pharyngeal arch artery morphology J:57677
abnormal iridocorneal angle J:61775
abnormal iris morphology J:61775
abnormal mesonephros morphology J:60834
abnormal pharyngeal arch artery morphology J:57677
abnormal pulmonary valve morphology J:57677
abnormal superior vena cava morphology J:57677
abnormal trabecular meshwork morphology J:61775
absent kidney J:60834
aortic arch coarctation J:57677
cornea ulcer J:61775
cornea vascularization J:61775
decreased angiogenesis J:57677
double ureter J:60834
duplex kidney J:60834
ectopic ureteric bud J:60834
enlarged liver J:57677
eyelids open at birth J:61775
hydronephrosis J:60834
hydrops fetalis J:57677
hydroureter J:60834
interrupted aortic arch, type b J:57677
iris stroma hypoplasia J:61775
lethality throughout fetal growth and development, incomplete penetrance J:57677
perimembraneous ventricular septal defect J:57677
renal hypoplasia J:60834
normal skeleton phenotype J:57677
thick aortic valve cusps J:57677
thick pulmonary valve cusps J:57677
trabecula carnea hypoplasia J:57677
ventricle myocardium hypoplasia J:57677
Foxc1tm1Blh/Foxc1+
Foxc2tm1Blh/Foxc2tm1Blh
involves: 129S6/SvEvTac 		abnormal mesonephros morphology J:91443
abnormal somite shape J:91443
Foxc1tm1Blh/Foxc1+
Foxc2tm1Blh/Foxc2tm1Blh
involves: 129S6/SvEvTac * Black Swiss 		abnormal pharyngeal arch artery morphology J:71693
abnormal somite shape J:71693
abnormal vascular development J:71693
absent second pharyngeal arch J:71693
decreased somite size J:71693
embryonic lethality during organogenesis, complete penetrance J:71693
enlarged third pharyngeal arch artery J:71693
Foxc1tm1Blh/Foxc1tm1Blh
Foxc2tm1Blh/Foxc2+
involves: 129S6/SvEvTac 		normal embryo phenotype J:91443
Foxc1tm1Blh/Foxc1tm1Blh
Foxc2tm1Blh/Foxc2+
involves: 129S6/SvEvTac * Black Swiss 		normal cardiovascular system phenotype J:71693
embryonic lethality during organogenesis, complete penetrance J:71693
Foxc1tm1Blh/Foxc1tm1Blh
Foxc2tm1Blh/Foxc2tm1Blh
involves: 129S6/SvEvTac 		abnormal mesonephros morphology J:91443
abnormal somite development J:91443
absent somites J:91443
normal embryo phenotype J:91443
Foxc1tm1Blh/Foxc1tm1Blh
Foxc2tm1Blh/Foxc2tm1Blh
involves: 129S6/SvEvTac * Black Swiss 		abnormal dorsal aorta morphology J:71693
abnormal dorsal-ventral polarity of the somites J:71693
abnormal head development J:71693
abnormal heartbeat J:71693
abnormal pharyngeal pouch morphology J:71693
abnormal vascular development J:71693
abnormal vitelline vascular remodeling J:71693
absent paraxial mesoderm J:71693
absent second pharyngeal arch J:71693
absent somites J:71693
decreased embryo size J:71693
dilated dorsal aorta J:71693
disorganized myocardium J:71693
embryonic lethality during organogenesis, complete penetrance J:71693
enlarged pericardium J:71693
head mesenchyme hypoplasia J:71693
incomplete rostral neuropore closure J:71693
small first pharyngeal arch J:71693
small heart J:71693
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory