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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Foxa1
forkhead box A1
MGI:1347472
19 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Foxa1tm1Gsc/Foxa1+
involves: 129P2/OlaHsd 		abnormal branching of the mammary ductal tree J:161401
increased mammary gland apoptosis J:161401
Foxa1tm1Gsc/Foxa1tm1Gsc
involves: 129P2/OlaHsd 		abnormal branching of the mammary ductal tree J:161401
Foxa1tm1Gsc/Foxa1tm1Gsc
involves: 129P2/OlaHsd * C57BL/6 		abnormal adrenal gland secretion J:53312
abnormal circulating insulin level J:53312
decreased circulating glucagon level J:53312
hypoglycemia J:53312
postnatal growth retardation J:53312
postnatal lethality, complete penetrance J:53312
Foxa1tm1Stf/Foxa1+
Not Specified 		decreased circulating HDL cholesterol level J:138581
Foxa1tm1Stf/Foxa1tm1Stf
Not Specified 		abnormal glucose homeostasis J:57493
decreased body weight J:57493
decreased circulating glucagon level J:57493
decreased circulating insulin level J:57493
decreased circulating triglyceride level J:57493
decreased insulin secretion J:57493
normal endocrine/exocrine gland phenotype J:57493
normal homeostasis/metabolism phenotype J:57493
hypoglycemia J:57493
impaired glucose tolerance J:57493
increased circulating cortisol level J:57493
increased circulating growth hormone level J:57493
postnatal growth retardation J:57493
postnatal lethality, complete penetrance J:57493
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory