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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Foxd3
forkhead box D3
MGI:1347473
43 phenotypes from 4 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Foxd3tm1.1Lby/Foxd3tm1.1Lby
either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * Black Swiss) or (involves: 129S6/SvEvTac * C57BL/6) or (involves: 129S6/SvEvTac * CD-1) 		abnormal cell proliferation J:79491
abnormal developmental patterning J:79491
abnormal embryonic epiblast morphology J:79491
abnormal extraembryonic endoderm formation J:79491
abnormal proximal-distal axis patterning J:79491
failure of primitive streak formation J:79491
failure to gastrulate J:79491
prenatal lethality, complete penetrance J:79491
Foxd3tm1Lby/Foxd3tm1Lby
either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * Black Swiss) or (involves: 129S6/SvEvTac * C57BL/6) or (involves: 129S6/SvEvTac * CD-1) 		abnormal anterior visceral endoderm cell migration J:79491
abnormal cell proliferation J:79491
abnormal developmental patterning J:79491
abnormal embryonic epiblast morphology J:79491
abnormal extraembryonic endoderm formation J:79491
abnormal proximal-distal axis patterning J:79491
absent mesoderm J:79491
decreased embryonic epiblast cell proliferation J:79491
embryonic lethality, complete penetrance J:79491
failure of primitive streak formation J:79491
failure to gastrulate J:79491
small embryonic epiblast J:79491
Foxd3tm1Lby/Foxd3tm1Lby
involves: 129S6/SvEvTac * CD-1 		abnormal placenta labyrinth morphology J:101652
abnormal trophoblast layer morphology J:101652
absent spongiotrophoblast J:101652
Foxd3tm2Lby/Foxd3tm2Lby
involves: 129S6/SvEvTac 		abnormal cell proliferation J:79491
abnormal developmental patterning J:79491
abnormal embryonic epiblast morphology J:79491
abnormal extraembryonic endoderm formation J:79491
abnormal proximal-distal axis patterning J:79491
embryonic lethality, complete penetrance J:79491
failure of primitive streak formation J:79491
failure to gastrulate J:79491
Foxd3tm2Lby/Foxd3tm2Lby
involves: 129S6/SvEvTac * CD-1 		abnormal placenta labyrinth morphology J:101652
abnormal trophoblast layer morphology J:101652
absent spongiotrophoblast J:101652
Foxd3tm2Lby/Foxd3tm3Lby
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S6/SvEvTac * C57BL/6 * CBA 		abnormal cardiac neural crest cell migration J:134482
abnormal common carotid artery morphology J:134482
abnormal cranium morphology J:134482
abnormal dorsal spinal root morphology J:134482
abnormal enteric nervous system morphology J:134482
abnormal enteric neural crest cell migration J:134482
abnormal heart development J:134482
abnormal spinal nerve morphology J:134482
absent frontal bone J:134482
absent nasal capsule J:134482
cleft palate J:134482
eyelids open at birth J:134482
increased apoptosis J:134482
increased hindbrain apoptosis J:134482
mandibular hyperostosis J:134482
midline facial cleft J:134482
perinatal lethality, complete penetrance J:134482
persistent truncus arteriosus J:134482
respiratory failure J:134482
short mandible J:134482
short maxilla J:134482
short premaxilla J:134482
small basioccipital bone J:134482
small dorsal root ganglion J:134482
small interparietal bone J:134482
small parietal bone J:134482
small pharyngeal arch J:134482
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory