Foxj1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Foxj1
forkhead box J1
MGI:1347474

62 phenotypes from 7 alleles in 11 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Foxj1^b2b774Clo/Foxj1^b2b774Clo C57BL/6J-Foxj1^b2b774Clo	heart left ventricle hypertrophy	J:175213
	heart right ventricle hypertrophy	J:175213
	heterotaxia	J:175213
	situs inversus totalis	J:175213
Foxj1^{tm1.1(cre/ERT2/GFP)Htg}/Foxj1^{tm1.1(cre/ERT2/GFP)Htg} involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J * C57BL/6NCr	hydrocephaly	J:213359
	situs inversus	J:213359
Foxj1^{tm1.1(cre/ERT2/GFP)Htg}/Foxj1^{tm1.1(cre/ERT2/GFP)Htg} STOCK Foxj1^{tm1.1(cre/ERT2/GFP)Htg}/J	abnormal cardiac outflow tract development	J:342078
	abnormal heart and great vessel attachment	J:342078
	abnormal heart looping	J:342078
	abnormal heart morphology	J:342078
	abnormal heart position or orientation	J:342078
	atrioventricular septal defect	J:342078
	dextrocardia	J:342078
	double inlet heart left ventricle	J:342078
	double outlet right ventricle	J:342078
	increased heart atrium size	J:342078
	ventricular septal defect	J:342078
Foxj1^tm1.1Ctk/Foxj1^tm1.2Ctk Tg(FOXJ1-cre/ERT2)1Blh/0 involves: C57BL/6 * DBA	abnormal neuron differentiation	J:174694
	abnormal rostral migratory stream morphology	J:174694
	hydrocephaly	J:174694
Foxj1^tm1.1Ctk/Foxj1^tm1.2Ctk Tg(FOXJ1-EGFP)85Leo/0 Tg(Nes-cre)1Kln/0 involves: C3H * C57BL/6 * C57BL/6J * SJL	abnormal neuron differentiation	J:174694
Foxj1^tm1.1Ctk/Foxj1^tm1.2Ctk Tg(Nes-cre)1Kln/0 involves: C57BL/6 * SJL	abnormal brain morphology	J:174694
	hydrocephaly	J:174694
Foxj1^tm1Bph/Foxj1^tm1Bph involves: 129S1/Sv * 129X1/SvJ * Black Swiss	abnormal choroid plexus morphology	J:50025
	abnormal left-right axis patterning	J:50025
	absent brain ependyma motile cilia	J:50025
	absent oviduct epithelium motile cilium	J:50025
	absent respiratory motile cilia	J:50025
	absent sperm flagellum	J:50025
	cachexia	J:50025
	decreased birth body size	J:50025
	decreased fetal weight	J:50025
	decreased locomotor activity	J:50025
	dextrocardia	J:50025
	fetal growth retardation	J:50025
	heterotaxia	J:50025
	hydrocephaly	J:50025
	infertility	J:50025
	lethality throughout fetal growth and development, incomplete penetrance	J:50025
	postnatal growth retardation	J:50025
	postnatal lethality, incomplete penetrance	J:50025
	situs inversus totalis	J:50025
	slow postnatal weight gain	J:50025
Foxj1^tm1Bph/Foxj1^tm1Bph involves: C57BL/6 * FVB/N	abnormal stomach position or orientation	J:104135
	aorta hypoplasia	J:104135
	normal cardiovascular system phenotype	J:104135
	lethality throughout fetal growth and development, incomplete penetrance	J:104135
	lung situs inversus	J:104135
	right pulmonary isomerism	J:104135
	right-sided stomach	J:104135
Foxj1^tm1Slb/Foxj1^tm1Slb involves: 129X1/SvJ	abnormal brain development	J:154976
	abnormal brain ependyma morphology	J:154976
	abnormal brain ventricle morphology	J:154976
	abnormal embryonic cilium location or orientation	J:182741
	abnormal olfactory bulb development	J:154976
	abnormal postnatal subventricular zone morphology	J:154976
	abnormal primitive node morphology	J:182741
	absent brain ependyma motile cilia	J:73616
	absent nodal flow	J:182741
	absent oviduct epithelium motile cilium	J:73616
	absent respiratory motile cilia	J:73616
	astrocytosis	J:154976
	decreased embryonic cilium length	J:182741
	dextrocardia	J:73616
	dilated lateral ventricle	J:73616
	hydrocephaly	J:73616, J:154976
	postnatal growth retardation	J:73616
	postnatal lethality, complete penetrance	J:73616, J:174694
	situs inversus	J:73616
	small olfactory bulb	J:154976
	transposition of great arteries	J:73616
Foxj1^tm1Slb/Foxj1^tm1Slb Tg(FOXJ1-EGFP)85Leo/0 involves: 129X1/SvJ * C3H * C57BL/6J	abnormal brain development	J:154976
	astrocytosis	J:154976
Tg(CD2-Foxj1)#Stlp/0 C57BL/6-Tg(CD2-Foxj1)#Stlp	abnormal T cell physiology	J:122222
	decreased CD4-positive, alpha-beta T cell number	J:122222
	decreased CD8-positive, alpha-beta T cell number	J:122222
	normal immune system phenotype	J:122222
	increased single-positive T cell number	J:122222
	lymphoid hypoplasia	J:122222

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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