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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Foxc2
forkhead box C2
MGI:1347481
85 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ednratm1Ywa/Ednratm1Ywa
Foxc2tm1Miu/Foxc2tm1Miu
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 		abnormal dorsal aorta morphology J:102130
dilated heart atrium J:102130
embryonic lethality during organogenesis, incomplete penetrance J:102130
pericardial edema J:102130
persistent truncus arteriosus J:102130
Foxc1tm1Blh/Foxc1+
Foxc2tm1Blh/Foxc2+
involves: 129S6/SvEvTac * Black Swiss 		abnormal aortic valve morphology J:57677
abnormal branching involved in ureteric bud morphogenesis J:60834
abnormal canal of Schlemm morphology J:61775
abnormal ciliary body morphology J:61775
abnormal cornea morphology J:61775
abnormal fourth pharyngeal arch artery morphology J:57677
abnormal iridocorneal angle J:61775
abnormal iris morphology J:61775
abnormal mesonephros morphology J:60834
abnormal pharyngeal arch artery morphology J:57677
abnormal pulmonary valve morphology J:57677
abnormal superior vena cava morphology J:57677
abnormal trabecular meshwork morphology J:61775
absent kidney J:60834
aortic arch coarctation J:57677
cornea ulcer J:61775
cornea vascularization J:61775
decreased angiogenesis J:57677
double ureter J:60834
duplex kidney J:60834
ectopic ureteric bud J:60834
enlarged liver J:57677
eyelids open at birth J:61775
hydronephrosis J:60834
hydrops fetalis J:57677
hydroureter J:60834
interrupted aortic arch, type b J:57677
iris stroma hypoplasia J:61775
lethality throughout fetal growth and development, incomplete penetrance J:57677
perimembraneous ventricular septal defect J:57677
renal hypoplasia J:60834
normal skeleton phenotype J:57677
thick aortic valve cusps J:57677
thick pulmonary valve cusps J:57677
trabecula carnea hypoplasia J:57677
ventricle myocardium hypoplasia J:57677
Foxc1tm1Blh/Foxc1+
Foxc2tm1Blh/Foxc2tm1Blh
involves: 129S6/SvEvTac 		abnormal mesonephros morphology J:91443
abnormal somite shape J:91443
Foxc1tm1Blh/Foxc1+
Foxc2tm1Blh/Foxc2tm1Blh
involves: 129S6/SvEvTac * Black Swiss 		abnormal pharyngeal arch artery morphology J:71693
abnormal somite shape J:71693
abnormal vascular development J:71693
absent second pharyngeal arch J:71693
decreased somite size J:71693
embryonic lethality during organogenesis, complete penetrance J:71693
enlarged third pharyngeal arch artery J:71693
Foxc1tm1Blh/Foxc1tm1Blh
Foxc2tm1Blh/Foxc2+
involves: 129S6/SvEvTac 		normal embryo phenotype J:91443
Foxc1tm1Blh/Foxc1tm1Blh
Foxc2tm1Blh/Foxc2+
involves: 129S6/SvEvTac * Black Swiss 		normal cardiovascular system phenotype J:71693
embryonic lethality during organogenesis, complete penetrance J:71693
Foxc1tm1Blh/Foxc1tm1Blh
Foxc2tm1Blh/Foxc2tm1Blh
involves: 129S6/SvEvTac 		abnormal mesonephros morphology J:91443
abnormal somite development J:91443
absent somites J:91443
normal embryo phenotype J:91443
Foxc1tm1Blh/Foxc1tm1Blh
Foxc2tm1Blh/Foxc2tm1Blh
involves: 129S6/SvEvTac * Black Swiss 		abnormal dorsal aorta morphology J:71693
abnormal dorsal-ventral polarity of the somites J:71693
abnormal head development J:71693
abnormal heartbeat J:71693
abnormal pharyngeal pouch morphology J:71693
abnormal vascular development J:71693
abnormal vitelline vascular remodeling J:71693
absent paraxial mesoderm J:71693
absent second pharyngeal arch J:71693
absent somites J:71693
decreased embryo size J:71693
dilated dorsal aorta J:71693
disorganized myocardium J:71693
embryonic lethality during organogenesis, complete penetrance J:71693
enlarged pericardium J:71693
head mesenchyme hypoplasia J:71693
incomplete rostral neuropore closure J:71693
small first pharyngeal arch J:71693
small heart J:71693
Foxc2tm1Miu/Foxc2tm1Miu
Pax1tm2Neu/Pax1tm2Neu
involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 		abnormal costovertebral joint morphology J:55575
abnormal dermomyotome development J:55575
abnormal dorsal aorta morphology J:55575
abnormal dorsal root ganglion morphology J:55575
abnormal muscle development J:55575
abnormal neural tube morphology J:55575
abnormal sclerotome morphology J:55575
abnormal subarachnoid space development J:55575
abnormal vertebrae development J:55575
abnormal vertebral body morphology J:55575
abnormal vertebral lamina morphology J:55575
abnormal vertebral pedicle morphology J:55575
absent intervertebral disk J:55575
decreased body length J:55575
fusion of atlas and odontoid process J:55575
meningomyelocele J:55575
perinatal lethality, incomplete penetrance J:55575
rib fusion J:55575
short vertebral column J:55575
spina bifida J:55575
vertebral fusion J:55575
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/09/2024
MGI 6.24 		The Jackson Laboratory