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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ror2
receptor tyrosine kinase-like orphan receptor 2
MGI:1347521
139 phenotypes from 7 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ror2em1(IMPC)Mbp/Ror2+
C57BL/6N-Ror2em1(IMPC)Mbp/MbpMmucd 		abnormal retina vasculature morphology J:211773
abnormal vitreous body morphology J:211773
cataract J:211773
increased grip strength J:211773
persistence of hyaloid vascular system J:211773
Ror2em1(IMPC)Mbp/Ror2em1(IMPC)Mbp
C57BL/6N-Ror2em1(IMPC)Mbp/MbpMmucd 		abnormal craniofacial morphology J:211773
abnormal limb morphology J:211773
abnormal placenta morphology J:211773
abnormal placenta vasculature J:211773
abnormal tail morphology J:211773
cleft palate J:211773
embryonic growth retardation J:211773
polydactyly J:211773
preweaning lethality, complete penetrance J:211773
Ror2tm1.2Meg/Ror2tm1.2Meg
involves: 129S4/SvJae * C57BL/6 * FVB/N 		abnormal facial morphology J:182150
caudal body truncation J:182150
short limbs J:182150
Ror2tm1Anec/Ror2+
B6.129S1-Ror2tm1Anec 		normal limbs/digits/tail phenotype J:134490
Ror2tm1Anec/Ror2tm1Anec
B6.129S1-Ror2tm1Anec 		abnormal axial skeleton morphology J:134490
abnormal bone mineralization J:134490
abnormal cartilage development J:134490
abnormal caudal vertebrae morphology J:134490
abnormal digit development J:134490
abnormal digit morphology J:134490
abnormal intervertebral disk morphology J:134490
abnormal limb development J:134490
abnormal limb morphology J:134490
abnormal nasal bone morphology J:134490
abnormal phalanx morphology J:134490
abnormal seminiferous tubule morphology J:134490
abnormal skeleton development J:134490
abnormal thoracic vertebrae morphology J:134490
abnormal vertebrae morphology J:134490
brachydactyly J:134490
brachyphalangia J:134490
broad nasal bone J:134490
caudal vertebral fusion J:134490
decreased body length J:134490
decreased body size J:134490
decreased bone trabecula number J:134490
decreased testis weight J:134490
decreased total body fat amount J:134490
decreased trabecular bone volume J:134490
delayed endochondral bone ossification J:134490
entropion J:134490
excessive tearing J:134490
normal homeostasis/metabolism phenotype J:134490
increased lean body mass J:134490
kinked tail J:134490
large orbits J:134490
oligozoospermia J:134490
reduced male fertility J:134490
rib fusion J:134490
short mandible J:134490
short metacarpal bones J:134490
short nasal bone J:134490
short snout J:134490
small seminiferous tubules J:134490
vertebral body hypoplasia J:134490
Ror2tm1Gdy/Ror2tm1Gdy
involves: 129P2/OlaHsd 		abnormal caudal vertebrae morphology J:60754
abnormal digit development J:134490
abnormal endochondral bone ossification J:60754
abnormal femur morphology J:60754
abnormal fibula morphology J:60754
abnormal hindlimb stylopod morphology J:134490
abnormal humerus morphology J:60754
abnormal limb development J:60754, J:134490
abnormal long bone epiphyseal plate morphology J:60754
abnormal long bone epiphyseal plate proliferative zone J:60754
abnormal long bone morphology J:60754
abnormal phalanx morphology J:60754
abnormal radius morphology J:60754
abnormal skeleton development J:134490
abnormal tail morphology J:60754
abnormal tibia morphology J:60754
abnormal ulna morphology J:60754
abnormal vertebrae morphology J:134490
abnormal vertebral column morphology J:60754
brachydactyly J:60754
cleft palate J:60754
delayed endochondral bone ossification J:60754, J:134490
increased width of hypertrophic chondrocyte zone J:60754
perinatal lethality, complete penetrance J:60754
rib fusion J:134490
short femur J:60754
short fibula J:60754
short humerus J:60754
short limbs J:60754
short lumbar vertebrae J:60754
short nasal bone J:134490
short radius J:60754
short snout J:60754
short tail J:60754
short tibia J:60754
short ulna J:60754
small caudal vertebrae J:60754
Ror2tm1Ymi/Ror2tm1Ymi
involves: 129P2/OlaHsd 		abnormal cochlear hair cell morphology J:140886
abnormal cochlear outer hair cell morphology J:140886
abnormal organ of Corti morphology J:140886
brachyphalangia J:134490
Ror2tm1Ymi/Ror2tm1Ymi
involves: 129P2/OlaHsd * C57BL/6 		abnormal autopod morphology J:88955
abnormal blood homeostasis J:60125
abnormal cartilage development J:60125
abnormal cartilage morphology J:60125
abnormal craniofacial development J:88955
abnormal cranium morphology J:88955
abnormal forelimb stylopod morphology J:88955
abnormal forelimb zeugopod morphology J:88955
abnormal hindlimb stylopod morphology J:88955
abnormal hindlimb zeugopod morphology J:88955
abnormal jaw morphology J:88955
abnormal limb morphology J:88955
abnormal long bone epiphyseal plate proliferative zone J:88955
abnormal malleus morphology J:88955
abnormal mandible morphology J:88955
abnormal mandibular angle morphology J:88955
abnormal mandibular condyloid process morphology J:88955
abnormal maxilla morphology J:88955
abnormal Meckel's cartilage morphology J:88955
abnormal middle ear ossicle morphology J:88955
abnormal nasal capsule morphology J:88955
abnormal primordial germ cell migration J:179805
abnormal pulmonary alveolus morphology J:60125
abnormal rib morphology J:60125
abnormal sacral vertebrae morphology J:88955
abnormal somite development J:88955
abnormal somite shape J:88955
abnormal somite size J:88955
abnormal tegmen tympani morphology J:88955
abnormal vertebrae development J:60125
abnormal vertebrae morphology J:88955
brachydactyly J:88955
cleft secondary palate J:88955
cyanosis J:60125
decreased embryo size J:60125, J:88955
decreased length of long bones J:88955
decreased primordial germ cell number J:179805
decreased width of hypertrophic chondrocyte zone J:88955
delayed bone ossification J:88955
delayed chondrocyte differentiation J:60125, J:88955
failure of palatal shelf elevation J:88955
genital tubercle hypoplasia J:88955
increased cranium width J:88955
midface hypoplasia J:88955
neonatal lethality, complete penetrance J:60125, J:88955
ocular hypertelorism J:88955
perimembraneous ventricular septal defect J:60125
polydactyly J:88955
respiratory distress J:60125
rib fusion J:60125
sacral vertebral fusion J:88955
short mandible J:88955
short Meckel's cartilage J:88955
short metacarpal bones J:88955
short radius J:88955
short tail J:88955
short ulna J:88955
small sacral vertebrae J:88955
small tail bud J:88955
transposition of great arteries J:60125
Ror2Tn(pb-ZG-s)1.1Mrc/Ror2Tn(pb-ZG-s)1.1Mrc
involves: C57BL/6J 		abnormal skeleton morphology J:123007
decreased birth body size J:123007
short limbs J:123007
short tail J:123007
Ror2Y324C/Ror2Y324C
involves: C57BL/6J 		abnormal hindgut morphology J:179805
abnormal primordial germ cell migration J:179805
abnormal reproductive system physiology J:179805
abnormal tail development J:179805
decreased primordial germ cell number J:179805
impaired somite development J:179805
increased primordial germ cell apoptosis J:179805
perinatal lethality J:179805
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory