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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Sdc2
syndecan 2
MGI:1349165
14 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Sdc2tm1b(KOMP)Wtsi/Sdc2tm1b(KOMP)Wtsi
C57BL/6N-Sdc2tm1b(KOMP)Wtsi/Ieg 		abnormal coat/hair pigmentation J:211773
abnormal lens morphology J:211773
aorta stenosis J:211773
decreased cardiac output J:211773
decreased red blood cell distribution width J:211773
decreased total retina thickness J:211773
increased circulating triglyceride level J:211773
Sdc2tm1c(KOMP)Wtsi/Sdc2tm1c(KOMP)Wtsi
Tg(Cdh5-cre/ERT2)1Rha/0
involves: C57BL/6J * C57BL/6N 		decreased angiogenesis J:276769
decreased susceptibility to injury J:276769
Sdc2tm1c(KOMP)Wtsi/Sdc2tm1c(KOMP)Wtsi
Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/0
involves: C57BL/6J * C57BL/6N * CBA 		abnormal retina vasculature morphology J:276769
decreased angiogenesis J:276769
decreased endothelial cell proliferation J:276769
decreased vascular endothelial cell proliferation J:276769
Sdc2tm1d(KOMP)Wtsi/Sdc2tm1d(KOMP)Wtsi
involves: C57BL/6J * C57BL/6N 		abnormal retina vasculature morphology J:276769
abnormal vascular endothelial cell physiology J:276769
decreased angiogenesis J:276769
decreased vascular endothelial cell proliferation J:276769
delayed wound healing J:276769
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory