Abcd1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Abcd1
ATP-binding cassette, sub-family D member 1
MGI:1349215

22 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Abcd1^tm1Kan/Y Gt(ROSA)26Sor^{tm2.1(CAG-ELOVL1)Geno}/Gt(ROSA)26Sor⁺ Tg(CMV-cre)1Cgn/0 involves: 129 * BALB/cJ * C57BL/6J * Swiss	increased fatty acids level	J:257393
	lethality, incomplete penetrance	J:257393
Abcd1^tm1Kan/Y Gt(ROSA)26Sor^{tm2.1(CAG-ELOVL1)Geno}/Gt(ROSA)26Sor⁺ Cnp^tm1(cre)Kan/Cnp⁺ involves: 129 * 129S1/Sv * 129X1/SvJ * C57BL/6J	increased fatty acids level	J:257393
Abcd1^tm1Kds/Abcd1^tm1Kds Slc27a2^tm1Kds/Slc27a2^tm1Kds involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6J	no abnormal phenotype detected	J:83438
Abcd1^tm1Kds/Y Abcd2^tm1Apuj/Abcd2^tm1Apuj involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6J	abnormal adrenal cortex morphology	J:94583
	abnormal astrocyte morphology	J:94583
	abnormal CNS glial cell morphology	J:104122
	abnormal involuntary movement	J:104122
	abnormal locomotor activation	J:94583
	abnormal locomotor behavior	J:104122
	abnormal microglial cell morphology	J:94583
	abnormal nerve conduction	J:94583
	abnormal nervous system electrophysiology	J:104122
	abnormal nervous system physiology	J:94583
	abnormal posture	J:104122
	astrocytosis	J:94583
	ataxia	J:104122
	axon degeneration	J:94583
	decreased vertical activity	J:104122
	impaired balance	J:104122
	impaired coordination	J:94583
	increased fatty acids level	J:94583, J:104122
	increased inflammatory response	J:94583
	tremors	J:104122
Abcd1^tm1Kds/Y Slc27a2^tm1Kds/Slc27a2^tm1Kds involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6J	no abnormal phenotype detected	J:83438

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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