Foxl2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Foxl2
forkhead box L2
MGI:1349428

48 phenotypes from 6 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Foxl2^{tm1(GFP/cre/ERT2)Pzg}/Foxl2⁺ involves: 129P2/OlaHsd * C57BL/6	no abnormal phenotype detected	J:159099
Foxl2^tm1Gpil/Foxl2^tm1Gpil either: 129S6/SvEvTac or (involves: 129S6/SvEvTac * C57BL/6J) or (involves: 129S6/SvEvTac * NIHS-BC)	abnormal eye morphology	J:90371
	abnormal ovary morphology	J:90371
	decreased body weight	J:90371
	decreased circulating insulin-like growth factor I level	J:90371
	eyelid hypoplasia	J:90371
	eyelids open at birth	J:90371
	female infertility	J:90371
	impaired ovarian folliculogenesis	J:90371
	postnatal lethality, incomplete penetrance	J:90371
Foxl2^tm1Tre/Foxl2⁺ involves: 129P2/OlaHsd * Black Swiss * CD-1	reduced female fertility	J:87737
Foxl2^tm1Tre/Foxl2^tm1Tre involves: 129P2/OlaHsd * Black Swiss * CD-1	absent mature ovarian follicles	J:87737
	absent primordial ovarian follicles	J:87737
	absent secondary ovarian follicles	J:87737
	decreased granulosa cell proliferation	J:87737
	female infertility	J:87737
	impaired granulosa cell differentiation	J:87737
	impaired ovarian folliculogenesis	J:87737
	increased atretic ovarian follicle number	J:87737
	postnatal lethality, incomplete penetrance	J:87737
	normal reproductive system phenotype	J:87737
	small ovary	J:87737
Foxl2^tm2.1Tre/Foxl2^tm2.1Tre Gnrhr^{tm1.1(cre)Uboe}/Gnrhr⁺ involves: 129S1/Sv * 129X1/SvJ	abnormal ovary physiology	J:204036
	abnormal seminiferous tubule morphology	J:204036
	abnormal spermatogenesis	J:204036
	abnormal testis physiology	J:204036
	arrest of male meiosis	J:204036
	arrest of spermatogenesis	J:204036
	asthenozoospermia	J:204036
	normal craniofacial phenotype	J:204036
	decreased circulating follicle stimulating hormone level	J:204036
	decreased circulating luteinizing hormone level	J:204036
	decreased corpora lutea number	J:204036
	decreased follicle stimulating hormone level	J:204036
	decreased litter size	J:204036
	decreased ovary weight	J:204036
	decreased ovulation rate	J:204036
	decreased Sertoli cell number	J:204036
	decreased testis weight	J:204036
	delayed vaginal opening	J:204036
	normal growth/size/body region phenotype	J:204036
	immotile sperm	J:204036
	impaired ovarian folliculogenesis	J:204036
	increased circulating luteinizing hormone level	J:204036
	oligozoospermia	J:204036
	prolonged estrus	J:204036
	reduced female fertility	J:204036
	reduced male fertility	J:204036
	small testis	J:204036
Foxl2^tm2.1Tre/Foxl2^tm2.1Tre Gt(ROSA)26Sor^{tm9(cre/ESR1)Arte}/? involves: 129S/Sv * C57BL/6	abnormal ovarian follicle morphology	J:157008
	abnormal ovary morphology	J:157008
	primary sex reversal	J:157008
Foxl2^tm2.1Tre/Foxl2^tm2.1Tre Tg(Cga-cre)3Sac/0 involves: C57BL/6 * SJL	abnormal ovarian follicle morphology	J:157008
	abnormal ovary morphology	J:157008
	abnormal ovary size	J:157008
	primary sex reversal	J:157008
Foxl2^tm2.1Tre/Foxl2^tm2.1Tre Tg(Gdf9-icre)5092Coo/0 involves: C57BL/6 * SJL	normal reproductive system phenotype	J:157008
Foxl2^tm3Tre/Foxl2^tm3Tre Not Specified	normal reproductive system phenotype	J:157008
Foxl2^tm4(cre)Tre/Foxl2⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	normal reproductive system phenotype	J:157008
Foxl2^tm4(cre)Tre/Foxl2^tm4(cre)Tre involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal ovarian follicle morphology	J:157008
	absent mature ovarian follicles	J:157008
	female infertility	J:157008
	impaired ovarian folliculogenesis	J:157008
	postnatal lethality	J:157008
	normal reproductive system phenotype	J:157008
	small ovary	J:157008

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