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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ppp2r5c
protein phosphatase 2, regulatory subunit B', gamma
MGI:1349475
38 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ppp2r5cem1(IMPC)Mbp/Ppp2r5cem1(IMPC)Mbp
C57BL/6N-Ppp2r5cem1(IMPC)Mbp/Ucd 		abnormal lymph node morphology J:211773
abnormal placement of pupils J:211773
abnormal spleen morphology J:211773
decreased circulating cholesterol level J:211773
decreased exploration in new environment J:211773
decreased grip strength J:211773
decreased lean body mass J:211773
decreased startle reflex J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
increased blood urea nitrogen level J:211773
increased circulating alkaline phosphatase level J:211773
increased heart weight J:211773
increased mean corpuscular hemoglobin J:211773
increased mean corpuscular volume J:211773
increased monocyte cell number J:211773
increased neutrophil cell number J:211773
increased total body fat amount J:211773
irregularly shaped pupil J:211773
preweaning lethality, incomplete penetrance J:211773
shortened QT interval J:211773
shortened ST segment J:211773
Ppp2r5cGt(XP0444)Wtsi/Ppp2r5c+
B6.129P2-Ppp2r5cGt(XP0444)Wtsi 		no abnormal phenotype detected J:210365
Ppp2r5cGt(XP0444)Wtsi/Ppp2r5cGt(XP0444)Wtsi
B6.129P2-Ppp2r5cGt(XP0444)Wtsi 		abnormal gait J:210365
abnormal interventricular septum morphology J:210365
abnormal Z line morphology J:210365
decreased body size J:210365
decreased body weight J:210365
decreased fetal cardiomyocyte number J:210365
decreased grip strength J:210365
decreased locomotor activity J:210365
impaired balance J:210365
increased fetal cardiomyocyte apoptosis J:210365
increased total body fat amount J:210365
neonatal lethality, incomplete penetrance J:210365
obese J:210365
pallor J:210365
thin interventricular septum J:210365
thin myocardium J:210365
ventricular septal defect J:210365
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory