Ing1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ing1
inhibitor of growth family, member 1
MGI:1349481

16 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ing1^{Gt(F066C08)Irpa}/Ing1^{Gt(F066C08)Irpa} involves: 129S2/SvPas	normal cellular phenotype	J:126798
	delayed cellular replicative senescence	J:126798
	increased fibroblast proliferation	J:126798
Ing1^{Gt(OST206270)Lex}/Ing1⁺ involves: 129S5/SvEvBrd * C57BL/6	increased B cell derived lymphoma incidence	J:118602
Ing1^{Gt(OST206270)Lex}/Ing1^{Gt(OST206270)Lex} involves: 129S5/SvEvBrd * C57BL/6	abnormal cell physiology	J:118602
	decreased body weight	J:118602
	decreased thymocyte number	J:118602
	increased B cell derived lymphoma incidence	J:118602
	increased cellular sensitivity to ionizing radiation	J:118602
	increased fibroblast apoptosis	J:118602
	increased fibroblast proliferation	J:118602
	increased thymocyte apoptosis	J:118602
Ing1^tm1Avg/Ing1^tm1Avg involves: 129S1/Sv * C57BL/6	abnormal cell cycle	J:105658
	abnormal maternal nurturing	J:105658
	decreased body weight	J:105658
	enlarged spleen	J:105658
	increased B cell derived lymphoma incidence	J:105658
	increased cellular sensitivity to ultraviolet irradiation	J:105658
	increased mortality induced by gamma-irradiation	J:105658
	premature death	J:105658

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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