Brd7 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Brd7
bromodomain containing 7
MGI:1349766

31 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Brd7^tm1.2Ligy/Brd7^tm1.2Ligy involves: 129S4/SvJaeSor * C57BL/6J * FVB/N	abnormal acrosome morphology	J:251649
	abnormal sperm head morphology	J:251649
	abnormal spermatid morphology	J:251649
	absent acrosome	J:251649
	arrest of spermatogenesis	J:251649
	azoospermia	J:251649
	decreased testis weight	J:251649
	globozoospermia	J:251649
	normal homeostasis/metabolism phenotype	J:251649
	increased male germ cell apoptosis	J:251649
	male infertility	J:251649
	small seminiferous tubules	J:251649
	small testis	J:251649
Brd7^tm1.2Ligy/Brd7^tm1.2Ligy involves: C57BL/6	abnormal dendrite morphology	J:223952
	abnormal long-term object recognition memory	J:223952
	abnormal social/conspecific interaction behavior	J:223952
	normal behavior/neurological phenotype	J:223952
	impaired short-term object recognition memory	J:223952
	impaired spatial learning	J:223952
	normal nervous system phenotype	J:223952
Brd7^{tm2a(EUCOMM)Wtsi}/Brd7⁺ Not Specified	abnormal behavior	J:175295
	abnormal coat/ hair morphology	J:175295
	decreased caudal vertebrae number	J:175295
	decreased circulating LDL cholesterol level	J:175295
	increased blood uric acid level	J:175295
	tremors	J:165965
Brd7^{tm2a(EUCOMM)Wtsi}/Brd7^{tm2a(EUCOMM)Wtsi} B6J.129S7-Brd7^{tm2a(EUCOMM)Wtsi}	abnormal blood vessel morphology	J:236093
	decreased fetal size	J:236093
	delayed limb development	J:236093
	fetal growth retardation	J:236093
	lethality throughout fetal growth and development, complete penetrance	J:236093

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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