About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Sec23b
SEC23 homolog B, COPII coat complex component
MGI:1350925
32 phenotypes from 4 alleles in 6 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Sec23bGt(AD0407)Wtsi/Sec23bGt(AD0407)Wtsi
129S1.129P2-Sec23bGt(AD0407)Wtsi 		abnormal suckling behavior J:186391
decreased birth weight J:186391
neonatal lethality, complete penetrance J:186391
Sec23bGt(AD0407)Wtsi/Sec23bGt(AD0407)Wtsi
B6J.129P2-Sec23bGt(AD0407)Wtsi 		abnormal endocrine pancreas development J:186391
abnormal endocrine pancreas morphology J:186391
abnormal exocrine pancreas physiology J:186391
abnormal intestinal goblet cell morphology J:186391
abnormal intestine morphology J:186391
abnormal pancreas morphology J:186391
abnormal pancreatic acinar cell morphology J:186391, J:237614
abnormal pancreatic acinus morphology J:186391
abnormal Paneth cell morphology J:186391
abnormal salivary gland morphology J:186391, J:237614
abnormal stomach glandular epithelium morphology J:186391
abnormal sublingual gland morphology J:186391
abnormal submandibular gland morphology J:186391
abnormal suckling behavior J:186391
absent pancreatic acinar cell zymogen granule J:186391
decreased birth weight J:186391
decreased circulating glucose level J:186391
decreased pancreatic acinar cell number J:186391
decreased pancreatic alpha cell number J:186391
decreased pancreatic beta cell number J:186391
decreased pancreatic islet number J:186391
gastric gland degeneration J:186391
normal hematopoietic system phenotype J:186391
normal homeostasis/metabolism phenotype J:237614
increased apoptosis J:186391
nasal gland degeneration J:186391
neonatal lethality, complete penetrance J:186391
pancreas degeneration J:186391
pancreas inflammation J:186391
pancreatic acinar hypoplasia J:186391
salivary gland degeneration J:186391
small pancreas J:186391
Sec23bGt(AD0407)Wtsi/Sec23bGt(AD0407)Wtsi
involves: 129P2/OlaHsd 		normal hematopoietic system phenotype J:213188
Sec23btm1a(EUCOMM)Wtsi/Sec23btm1a(EUCOMM)Wtsi
involves: C57BL/6J * C57BL/6N 		gastric gland degeneration J:186391
nasal gland degeneration J:186391
neonatal lethality, complete penetrance J:186391
pancreas degeneration J:186391
salivary gland degeneration J:186391
Sec23btm1b(EUCOMM)Wtsi/Sec23btm1b(EUCOMM)Wtsi
involves: C57BL/6J * C57BL/6N * FVB/N 		gastric gland degeneration J:186391
nasal gland degeneration J:186391
neonatal lethality, complete penetrance J:186391
pancreas degeneration J:186391
salivary gland degeneration J:186391
Sec23btm1d(EUCOMM)Wtsi/Sec23btm1d(EUCOMM)Wtsi
involves: C57BL/6 * C57BL/6N * FVB/N * SJL 		normal hematopoietic system phenotype J:213188
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory