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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tlx2
T cell leukemia, homeobox 2
MGI:1350935
21 phenotypes from 4 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Tlx2tm1.1(cre)Rpk/Tlx2tm1.1(cre)Rpk
involves: 129S4/SvJae * C57BL/6 		abnormal small intestine morphology J:148830
distended abdomen J:148830
distended cecum J:148830
megacolon J:148830
premature death J:148830
Tlx2tm1Htno/Tlx2tm1Htno
involves: 129S1/Sv * 129X1/SvJ 		abnormal colon morphology J:42356
abnormal enteric ganglia morphology J:42356
abnormal enteric nervous system morphology J:42356
abnormal innervation J:42356
abnormal large intestine morphology J:42356
abnormal small intestine morphology J:42356
decreased survivor rate J:42356
distended abdomen J:42356
megacolon J:42356
premature death J:42356
Tlx2tm1Sjk/Tlx2tm1Sjk
involves: 129/Sv * C57BL/6 		abnormal enteric ganglia morphology J:40722
abnormal enteric neuron morphology J:40722
abnormal large intestine morphology J:40722
abnormal small intestine morphology J:40722
distended abdomen J:40722
distended cecum J:40722
distended ileum J:40722
megacolon J:40722
normal nervous system phenotype J:40722
postnatal growth retardation J:40722
premature death J:40722
Tlx2tm1Ut/Tlx2tm1Ut
involves: 129S1/Sv * 129X1/SvJ * CD-1 		abnormal amnion morphology J:48372
abnormal ectoderm development J:48372
abnormal embryonic tissue morphology J:48372
abnormal extraembryonic tissue morphology J:48372
abnormal primitive streak formation J:48372
embryonic lethality between implantation and somite formation, complete penetrance J:48372
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory