Podxl Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Podxl
podocalyxin-like
MGI:1351317

24 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Podxl^em1(IMPC)H/Podxl⁺ C57BL/6N-Podxl^em1(IMPC)H/H	abnormal retina morphology	J:211773
	decreased hemoglobin content	J:211773
	increased red blood cell distribution width	J:211773
Podxl^em1(IMPC)H/Podxl^em1(IMPC)H C57BL/6N-Podxl^em1(IMPC)H/H	preweaning lethality, complete penetrance	J:211773
Podxl^tm1Kmn/Podxl⁺ either: (involves: 129P2/OlaHsd * BALB/c) or (involves: 129P2/OlsHsd * C57BL/6)	omphalocele	J:70294
Podxl^tm1Kmn/Podxl^tm1Kmn either: (involves: 129P2/OlaHsd * BALB/c) or (involves: 129P2/OlsHsd * C57BL/6)	absent podocyte foot process	J:70294
	absent podocyte slit diaphragm	J:70294
	anuria	J:70294
	hydrops fetalis	J:70294
	increased systemic arterial blood pressure	J:70294
	neonatal lethality, complete penetrance	J:70294
	omphalocele	J:70294
Podxl^tm1Parl/Podxl⁺ Tg(Mylpf-cre)3Kraj/? involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * FVB/N	no abnormal phenotype detected	J:158322
Podxl^tm1Parl/Podxl^tm1Parl Tg(Mylpf-cre)3Kraj/? involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * FVB/N	abnormal capillary morphology	J:158322
	abnormal carotid artery morphology	J:158322
	enlarged brain ventricles	J:158322
Podxl^tm2Kmn/Podxl^tm2Kmn B6.129(SJL)-Podxl^tm2Kmn	no abnormal phenotype detected	J:223453
Podxl^tm2Kmn/Podxl^tm2Kmn Tg(Cdh5-cre)7Mlia/0 B6.Cg-Podxl^tm2Kmn Tg(Cdh5-cre)7Mlia	abnormal lung morphology	J:223453
	abnormal lung volume	J:223453
	abnormal pulmonary collagen fibril morphology	J:223453
	abnormal pulmonary elastic fiber morphology	J:223453
	decreased lung endothelial cell adhesion	J:223453
	increased airway resistance	J:223453
	increased lung endothelial cell adhesion	J:223453
	increased vascular permeability	J:223453
	overexpanded pulmonary alveolus	J:223453

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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