Syn3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Syn3
synapsin III
MGI:1351334

21 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Syn3^{tm1.1(KOMP)Vlcg}/Syn3^{tm1.1(KOMP)Vlcg} C57BL/6N-Syn3^{tm1.1(KOMP)Vlcg}/J	abnormal bone structure	J:211773
	abnormal motor coordination/balance	J:211773
	decreased bone mineral content	J:211773
	decreased bone mineral density	J:211773
	decreased erythrocyte cell number	J:211773
	decreased hematocrit	J:211773
	decreased hemoglobin content	J:211773
	decreased thigmotaxis	J:211773
	hyperactivity	J:211773
	increased circulating alanine transaminase level	J:211773
	increased circulating sodium level	J:211773
	increased grip strength	J:211773
	increased heart rate variability	J:211773
Syn3^tm1Pggd/Syn3^tm1Pggd B6.129X1-Syn3^tm1Jfe	abnormal social investigation	J:201707
	decreased aggression towards mice	J:201707
	impaired social transmission of food preference	J:201707
	normal taste/olfaction phenotype	J:201707
Syn3^tm1Pggd/Syn3^tm1Pggd involves: 129X1/SvJ	abnormal inhibitory postsynaptic currents	J:77048
	delayed axon extension	J:77048
	increased excitatory postsynaptic current amplitude	J:77048
	increased synaptic depression	J:77048

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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