Grm2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Grm2
glutamate receptor, metabotropic 2
MGI:1351339

11 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Grm2^tm1Ddsc/Grm2^tm1Ddsc involves: 129S1/Sv * 129X1/SvJ * CD-1	abnormal anxiety-related response	J:113260
Grm2^tm1Nak/Grm2^tm1Nak B6.129S-Grm2^tm1Nak	abnormal GABAergic neuron physiology	J:202321
	abnormal motor capabilities/coordination/movement	J:97172
	cocaine preference	J:97172
	decreased susceptibility to neuronal excitotoxicity	J:202321
	impaired coordination	J:97172
	increased dopamine level	J:97172
	increased locomotor activity	J:97172
	normal nervous system phenotype	J:202321
Grm2^tm1Nak/Grm2^tm1Nak involves: 129S/SvEv	abnormal excitatory postsynaptic potential	J:34606
Grm2^tm1Nak/Grm2^tm1Nak involves: 129S/SvEv	reduced long-term depression	J:34606

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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