Grm5 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Grm5
glutamate receptor, metabotropic 5
MGI:1351342

24 phenotypes from 6 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Grm5^tm1.1Jixu/Grm5^tm1.1Jixu involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6	normal behavior/neurological phenotype	J:147275
Grm5^tm1.1Kksz/Grm5^tm1.1Kksz involves: 129S1/Sv * 129X1/SvJ	abnormal nociception after inflammation	J:191366
Grm5^tm1.1Kksz/Grm5^tm1.1Kksz involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	decreased alcohol consumption	J:151084
Grm5^tm1.2Jixu/Grm5^tm1.2Jixu involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6	abnormal contextual conditioning behavior	J:147275
	abnormal cued conditioning behavior	J:147275
	abnormal inhibitory learning	J:147275
	abnormal latent inhibition of conditioning behavior	J:147275
Grm5^tm1Dgen/Grm5^tm1Dgen involves: 129P2/OlaHsd * C57BL/6J	abnormal motor coordination/balance	J:82809
	decreased body weight	J:82809
	decreased susceptibility to pharmacologically induced seizures	J:82809
	decreased total body fat amount	J:82809
	increased susceptibility to pharmacologically induced seizures	J:82809
	increased thermal nociceptive threshold	J:82809
Grm5^tm1Fcq/Grm5^tm1Fcq Not Specified	abnormal cocaine consumption	J:97288
	impaired behavioral response to cocaine	J:97288
	reduced long-term potentiation	J:97042
Grm5^tm1Rod/Grm5⁺ involves: 129 * C57BL/6 * FVB	abnormal nerve fiber response	J:127792
Grm5^tm1Rod/Grm5^tm1Rod B6.129-Grm5^tm1Rod	abnormal associative learning	J:268239
	cognitive inflexibility	J:268239
	impaired discrimination learning	J:268239
	impaired learning	J:268239
Grm5^tm1Rod/Grm5^tm1Rod B6.129-Grm5^tm1Rod/J	abnormal locomotor activation	J:102700
Grm5^tm1Rod/Grm5^tm1Rod involves: 129S1/Sv * 129X1/SvJ * CD-1	abnormal contextual conditioning behavior	J:41096
	abnormal excitatory postsynaptic potential	J:41096
	abnormal spatial learning	J:41096
	reduced long-term potentiation	J:41096

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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