Grm8 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Grm8
glutamate receptor, metabotropic 8
MGI:1351345

10 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Grm8^tm1Dgen/Grm8^tm1Dgen involves: 129P2/OlaHsd * C57BL/6J	abnormal locomotor behavior	J:82809
Grm8^tm1Dgen/Grm8^tm1Dgen involves: 129P2/OlaHsd * C57BL/6J	decreased prepulse inhibition	J:82809
Grm8^tm1Duv/Grm8^tm1Duv B6.129S1-Grm8^tm1Duv	decreased exploration in new environment	J:101087
	impaired swimming	J:101087
	increased anxiety-related response	J:101087
	increased body weight	J:101087
	increased percent body fat/body weight	J:101087
	insulin resistance	J:101087
Grm8^tm1En/Grm8^tm1En involves: 129S1/Sv * 129X1/SvJ * C57BL/6	decreased physiological sensitivity to xenobiotic	J:97019
Grm8^{tm2a(KOMP)Wtsi}/Grm8^{tm2a(KOMP)Wtsi} C57BL/6N-Grm8^{tm2a(KOMP)Wtsi}/Wtsi	abnormal retina morphology	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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