Dok3 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dok3
docking protein 3
MGI:1351490

8 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dok3^tm1Brs/Dok3^tm1Brs involves: C57BL/6	increased macrophage cell number	J:163407
Dok3^tm1Kplm/Dok3^tm1Kplm involves: 129P2/OlaHsd	abnormal B cell calcium ion homeostasis	J:280795
	abnormal B cell physiology	J:280795
	enhanced humoral immune response	J:280795
	increased B cell proliferation	J:280795
	increased IgG3 level	J:280795
	increased IgM level	J:280795
Dok3^tm1Ppp/Dok3^tm1Ppp 129S1/Sv-Dok3^tm1Ppp	increased lung adenocarcinoma incidence	J:158011

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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