Dok3 Phenotype Annotations - Multigenic Genotypes

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dok3
docking protein 3
MGI:1351490

13 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Dok1^tm1Ppp/Dok1^tm1Ppp Dok2^tm1Ppp/Dok2^tm1Ppp Dok3^tm1Ppp/Dok3^tm1Ppp 129S1/Sv-Dok1^tm1Ppp Dok2^tm1Ppp Dok3^tm1Ppp	abnormal pulmonary alveolus morphology	J:158011
	increased bronchioalveolar stem cell number	J:158011
	increased chronic myelocytic leukemia incidence	J:158011
	increased leukocyte cell number	J:158011
	increased lung adenocarcinoma incidence	J:158011
	increased lung tumor incidence	J:158011
	increased type II pneumocyte number	J:158011
	premature death	J:158011
	pulmonary hyperplasia	J:158011
Dok1^tm1Ppp/Dok1^tm1Ppp Dok3^tm1Ppp/Dok3^tm1Ppp 129S1/Sv-Dok1^tm1Ppp Dok3^tm1Ppp	increased lung adenocarcinoma incidence	J:158011
Dok1^tm1Yyam/Dok1^tm1Yyam Dok2^tm1Yyam/Dok2^tm1Yyam Dok3^tm1Brs/Dok3^tm1Brs involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6	abnormal macrophage physiology	J:163407
	increased histiocytic sarcoma incidence	J:163407
	increased macrophage cell number	J:163407
	increased tumor incidence	J:163407
	premature death	J:163407

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24