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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Dguok
deoxyguanosine kinase
MGI:1351602
41 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Dguokem1(IMPC)J/Dguokem1(IMPC)J
C57BL/6NJ-Dguokem1(IMPC)J/Mmjax 		abnormal locomotor behavior J:211773
decreased bone mineral density J:211773
decreased exploration in new environment J:211773
decreased lean body mass J:211773
decreased locomotor activity J:211773
female infertility J:211773
increased bone mineral content J:211773
increased grip strength J:211773
increased total body fat amount J:211773
Dguoktm1.1Anka/Dguoktm1.1Anka
involves: 129 * C57BL/6N 		abnormal hepatocyte morphology J:294620
abnormal lipid metabolism J:294620
abnormal liver physiology J:294620
abnormal mitochondrial ATP synthesis coupled electron transport J:294620
abnormal mitochondrial crista morphology J:294620
abnormal mitochondrial shape J:294620
abnormal redox activity J:294620
absent subcutaneous adipose tissue J:294620
normal behavior/neurological phenotype J:294620
decreased body size J:294620
decreased body weight J:294620
decreased circulating glucose level J:294620
decreased circulating serum albumin level J:294620
decreased hepatocyte mitochondrial DNA content J:294620
decreased mitochondrial DNA content J:294620
decreased myocardial fiber mitochondrial DNA content J:294620
decreased skeletal muscle fiber mitochondrial DNA content J:294620
decreased total body fat amount J:294620
dilated mitochondrion J:294620
enhanced liver regeneration J:294620
grizzled coat color J:294620
increased circulating alanine transaminase level J:294620
increased circulating aspartate transaminase level J:294620
increased circulating cholesterol level J:294620
increased heart weight J:294620
increased hepatocyte karyomegaly J:294620
increased hepatocyte proliferation J:294620
increased kidney weight J:294620
increased liver weight J:294620
oxidative stress J:294620
premature death J:294620
weight loss J:294620
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory