About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Npas3
neuronal PAS domain protein 3
MGI:1351610
43 phenotypes from 4 alleles in 4 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Npas3tm1b(KOMP)Wtsi/Npas3+
C57BL/6N-Npas3tm1b(KOMP)Wtsi/Kmpc 		increased startle reflex J:211773
no spontaneous movement J:211773
unresponsive to tactile stimuli J:211773
Npas3tm1b(KOMP)Wtsi/Npas3tm1b(KOMP)Wtsi
C57BL/6N-Npas3tm1b(KOMP)Wtsi/Kmpc 		no spontaneous movement J:211773
preweaning lethality, complete penetrance J:211773
unresponsive to tactile stimuli J:211773
Npas3tm1Ewb/Npas3tm1Ewb
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal behavioral response to xenobiotic J:101561
abnormal cerebellar foliation J:101561
abnormal cingulate gyrus morphology J:101561
abnormal corpus callosum morphology J:101561
abnormal gait J:101561
abnormal hippocampus morphology J:101561
abnormal nest building behavior J:101561
abnormal reflex J:101561
abnormal response to novel object J:101561
abnormal response to novelty J:101561
abnormal retrosplenial region morphology J:101561
abnormal startle reflex J:101561
decreased anxiety-related response J:101561
decreased body weight J:101561
enlarged cerebral aqueduct J:101561
enlarged fourth ventricle J:101561
enlarged lateral ventricles J:101561
enlarged third ventricle J:101561
impaired coordination J:101561
increased exploration in new environment J:101561
limb grasping J:101561
short stride length J:101561
Npas3tm1Mesu/Npas3+
B6.129S6-Npas3tm1Mesu 		abnormal lung vasculature morphology J:150793
emphysema J:150793
impaired lung alveolus development J:150793
increased airway resistance J:150793
overexpanded pulmonary alveolus J:150793
Npas3tm1Mesu/Npas3tm1Mesu
B6.129S6-Npas3tm1Mesu 		abnormal pulmonary alveolar parenchyma morphology J:150793
bronchiectasis J:150793
cyanosis J:150793
dilated respiratory conducting tube J:150793
impaired branching involved in trachea morphogenesis J:150793
overexpanded pulmonary alveolus J:150793
postnatal lethality, incomplete penetrance J:150793
respiratory distress J:150793
Npas3tm1Slm/Npas3tm1Slm
involves: 129S/SvEv * C57BL/6 		abnormal maternal nurturing J:92610
abnormal social investigation J:92610
decreased body size J:92610
hyperactivity J:92610
short stride length J:92610
stereotypic behavior J:92610
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory