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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Exoc6
exocyst complex component 6
MGI:1351611
31 phenotypes from 2 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Exoc6hbd/Exoc6hbd
AB.Cg-Exoc6hbd 		abnormal enzyme/coenzyme activity J:8251
anisocytosis J:8251
decreased erythrocyte osmotic fragility J:8251
decreased hemoglobin content J:8251
decreased mean corpuscular hemoglobin J:8251
decreased spleen iron level J:8251
enlarged spleen J:8251
increased circulating iron level J:8251
increased erythrocyte protoporphyrin level J:8251
microcytic anemia J:8251
microcytosis J:8251
poikilocytosis J:8251
polychromatophilia J:8251
reticulocytosis J:8251
Exoc6hbd/Exoc6hbd
B6.Cg-Exoc6hbd/J 		abnormal erythrocyte morphology J:105712
abnormal erythropoiesis J:42436
abnormal iron homeostasis J:105712
decreased hematocrit J:42436, J:105712
decreased hemoglobin content J:42436, J:105712
decreased mean corpuscular hemoglobin concentration J:42436
decreased mean corpuscular volume J:42436, J:105712
increased erythrocyte protoporphyrin level J:42436
microcytic anemia J:42436, J:105712
microcytosis J:42436
Exoc6hbd/Exoc6hbd
involves: STOCK Ay 		abnormal proerythroblast morphology J:5439
decreased erythrocyte cell number J:5439
decreased erythrocyte osmotic fragility J:5439
decreased mean corpuscular hemoglobin J:5439
hyperchromasia J:5439
hypochromic anemia J:5439
increased mean corpuscular volume J:5439
macrocytosis J:5439
polychromatophilia J:5439
preweaning lethality, incomplete penetrance J:5439
Exoc6tm1b(EUCOMM)Wtsi/Exoc6+
C57BL/6N-Exoc6tm1b(EUCOMM)Wtsi/Bay 		hyperactivity J:211773
unresponsive to tactile stimuli J:211773
Exoc6tm1b(EUCOMM)Wtsi/Exoc6tm1b(EUCOMM)Wtsi
C57BL/6N-Exoc6tm1b(EUCOMM)Wtsi/Bay 		abnormal skin appearance J:211773
pallor J:211773
preweaning lethality, incomplete penetrance J:211773
unresponsive to tactile stimuli J:211773
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory