Sh2d3c Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sh2d3c
SH2 domain containing 3C
MGI:1351631

23 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sh2d3c^tm1.1Ebp/Sh2d3c^tm1.1Ebp involves: C57BL/6	abnormal axon extension	J:164874
	abnormal nervous system physiology	J:164874
	abnormal olfactory bulb glomerular layer morphology	J:164874
	abnormal olfactory bulb layer morphology	J:164874
	abnormal olfactory bulb mitral cell layer morphology	J:164874
	abnormal olfactory nerve morphology	J:164874
	abnormal sensory neuron innervation pattern	J:164874
	abnormal sensory neuron morphology	J:164874
	absent gastric milk in neonates	J:165694
	decreased gonadotropin-releasing hormone neuron number	J:164874
	neonatal lethality, incomplete penetrance	J:164874, J:165694
	olfactory bulb hypoplasia	J:164874
	small testis	J:164874
Sh2d3c^tm1Lex/Sh2d3c^tm1Lex involves: 129S5/SvEvBrd * C57BL/6	abnormal B cell physiology	J:161448
	abnormal humoral immune response	J:161448
	abnormal leukocyte migration	J:161448
	abnormal marginal zone B cell physiology	J:161448
	decreased IgG1 level	J:161448
	decreased IgG2b level	J:161448
	decreased IgG3 level	J:161448
	decreased IgM level	J:161448
	decreased interleukin-6 secretion	J:161448
	decreased marginal zone B cell number	J:161448

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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