Ip6k1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ip6k1
inositol hexaphosphate kinase 1
MGI:1351633

18 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ip6k1^em1Seyk/Ip6k1^em1Seyk C57BL/6-Ip6k1^em1Seyk	abnormal endocytosis	J:306957
	abnormal protein level	J:306957
	abnormal synaptic vesicle exocytosis	J:306957
	abnormal synaptic vesicle recycling	J:306957
	decreased excitatory postsynaptic current amplitude	J:306957
	decreased paired-pulse facilitation	J:306957
	enhanced paired-pulse facilitation	J:306957
	normal nervous system phenotype	J:306957
Ip6k1^{Gt(OST137568)Lex}/Ip6k1^{Gt(OST137568)Lex} involves: 129S5/SvEvBrd * C57BL/6J	azoospermia	J:103485
	decreased circulating insulin level	J:103485
	impaired glucose tolerance	J:103485
	testis degeneration	J:103485
Ip6k1^tm1.1Snyd/Ip6k1^tm1.1Snyd involves: 129X1/SvJ * BALB/c * C57BL/6	abnormal spermatid morphology	J:132167
	abnormal spermiogenesis	J:132167
	azoospermia	J:132167
	decreased body size	J:132167
	decreased circulating insulin level	J:132167
	increased insulin sensitivity	J:132167
	male infertility	J:132167
	postnatal growth retardation	J:132167

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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