Abcc6 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Abcc6
ATP-binding cassette, sub-family C member 6
MGI:1351634

14 phenotypes from 9 alleles in 19 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Abcc6^{Dyscalc1-C3H/DiSnA}/Abcc6^{Dyscalc1-C57BL/10} involves: C3H/DiSnA * C57BL/10	decreased susceptibility to dystrophic cardiac calcinosis	J:76777
Abcc6^{Dyscalc1-C3H/HeNCrl}/Abcc6^{Dyscalc1-C3H/HeNCrl} involves: C3H/HeNCrl * C57BL/6NCrl	increased susceptibility to dystrophic cardiac calcinosis	J:109580
Abcc6^{Dyscalc1-C57BL/6J}/Abcc6^{Dyscalc1-C57BL/6J} involves: C3H/HeJ * C57BL/6J	decreased susceptibility to dystrophic cardiac calcinosis	J:72021
Abcc6^{Dyscalc1-C57BL/10}/Abcc6^{Dyscalc1-C57BL/10} involves: C3H/DiSnA * C57BL/10	decreased susceptibility to dystrophic cardiac calcinosis	J:76777
Abcc6^{Dyscalc1-DBA/2J}/Abcc6^{Dyscalc1-DBA/2J} involves: C57BL/6J * DBA/2J	increased susceptibility to dystrophic cardiac calcinosis	J:76777
Abcc6^rs32756904-T/Abcc6^{Dyscalc1-C57BL/6J} involves: C3H/HeJ * C57BL/6J	decreased susceptibility to dystrophic cardiac calcinosis	J:72021
Abcc6^rs32756904-T/Abcc6^rs32756904-T involves: C3H/HeJ * C57BL/6J	increased susceptibility to dystrophic cardiac calcinosis	J:33253, J:72021
Abcc6^tm1Aabb/Abcc6^tm1Aabb involves: 129P2/OlaHsd * C57BL/6	abnormal Bruch membrane morphology	J:105062
	abnormal kidney vasculature morphology	J:105062
	calcified artery	J:105062
	calcified skin	J:105062
	decreased circulating HDL cholesterol level	J:105062
	increased circulating creatinine level	J:105062
Abcc6^{tm1c(EUCOMM)Wtsi}/Abcc6^{tm1c(EUCOMM)Wtsi} E2f1^{Tg(Wnt1-cre)2Sor}/? B6.Cg-E2f1^{Tg(Wnt1-cre)2Sor} Abcc6^{tm1c(EUCOMM)Wtsi}	abnormal snout skin morphology	J:252837
	calcified skin	J:252837
	calcinosis	J:252837
Abcc6^{tm1c(EUCOMM)Wtsi}/Abcc6^{tm1c(EUCOMM)Wtsi} E2f1^{Tg(Wnt1-cre)2Sor}/? Speer6-ps1^{Tg(Alb-cre)21Mgn}/? B6.Cg-E2f1^{Tg(Wnt1-cre)2Sor} Abcc6^{tm1c(EUCOMM)Wtsi} Speer6-ps1^{Tg(Alb-cre)21Mgn}	abnormal snout skin morphology	J:252837
	calcified skin	J:252837
	calcinosis	J:252837
Abcc6^{tm1c(EUCOMM)Wtsi}/Abcc6^{tm1c(EUCOMM)Wtsi} Pax7^tm1(cre)Mrc/? B6.Cg-Pax7^tm1(cre)Mrc Abcc6^{tm1c(EUCOMM)Wtsi}	normal integument phenotype	J:252837
Abcc6^{tm1c(EUCOMM)Wtsi}/Abcc6^{tm1c(EUCOMM)Wtsi} Ptprc^tm1(cre)Medv/? B6.Cg-Ptprc^tm1(cre)Medv Abcc6^{tm1c(EUCOMM)Wtsi}	normal integument phenotype	J:252837
Abcc6^{tm1c(EUCOMM)Wtsi}/Abcc6^{tm1c(EUCOMM)Wtsi} Speer6-ps1^{Tg(Alb-cre)21Mgn}/? B6.Cg-Abcc6^{tm1c(EUCOMM)Wtsi} Speer6-ps1^{Tg(Alb-cre)21Mgn}	abnormal snout skin morphology	J:252837
	calcified skin	J:252837
	calcinosis	J:252837
Abcc6^{tm1c(EUCOMM)Wtsi}/Abcc6^{tm1c(EUCOMM)Wtsi} Speer6-ps1^{Tg(Alb-cre)21Mgn}/? Tg(Cdx1-cre)23Kem/? B6.Cg-Abcc6^{tm1c(EUCOMM)Wtsi} Speer6-ps1^{Tg(Alb-cre)21Mgn} Tg(Cdx1-cre)23Kem	abnormal snout skin morphology	J:252837
	calcified skin	J:252837
	calcinosis	J:252837
Abcc6^{tm1c(EUCOMM)Wtsi}/Abcc6^{tm1c(EUCOMM)Wtsi} Tg(Cdh5-cre)7Mlia/? B6.Cg-Abcc6^{tm1c(EUCOMM)Wtsi} Tg(Cdh5-cre)7Mlia	normal integument phenotype	J:252837
Abcc6^{tm1c(EUCOMM)Wtsi}/Abcc6^{tm1c(EUCOMM)Wtsi} Tg(Cdh16-cre)91Igr/? B6.Cg-Abcc6^{tm1c(EUCOMM)Wtsi} Tg(Cdh16-cre)91Igr	normal integument phenotype	J:252837
Abcc6^{tm1c(EUCOMM)Wtsi}/Abcc6^{tm1c(EUCOMM)Wtsi} Tg(CMV-cre)1Cgn/? B6.Cg-Abcc6^{tm1c(EUCOMM)Wtsi} Tg(CMV-cre)1Cgn	abnormal snout skin morphology	J:252837
	calcified skin	J:252837
	calcinosis	J:252837
Abcc6^{tm1c(EUCOMM)Wtsi}/Abcc6^{tm1c(EUCOMM)Wtsi} Tg(Fabp4-cre)1Rev/? B6.Cg-Abcc6^{tm1c(EUCOMM)Wtsi} Tg(Fabp4-cre)1Rev	normal integument phenotype	J:252837
Abcc6^{tm1c(EUCOMM)Wtsi}/Abcc6^{tm1c(EUCOMM)Wtsi} Tg(Pdgfrb-cre)35Vli/? B6.Cg-Abcc6^{tm1c(EUCOMM)Wtsi} Tg(Pdgfrb-cre)35Vli	normal integument phenotype	J:252837
Abcc6^{tm1c(EUCOMM)Wtsi}/Abcc6^{tm1c(EUCOMM)Wtsi} Tg(Tagln-cre)1Her/? B6.Cg-Abcc6^{tm1c(EUCOMM)Wtsi} Tg(Tagln-cre)1Her	normal integument phenotype	J:252837
Abcc6^tm1Jfk/Abcc6^tm1Jfk B6.129S1-Abcc6^tm1Jfk	abnormal snout skin morphology	J:252837
	calcified skin	J:252837
	calcinosis	J:252837
Abcc6^tm1Jfk/Abcc6^tm1Jfk involves: 129S1/Sv * C57BL/6J	abnormal vibrissa follicle morphology	J:101372
	calcified artery	J:101372
	calcified retina	J:101372
	calcified skin	J:101372
	calcinosis	J:101372
	nephrocalcinosis	J:101372

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