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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Magel2
MAGE family member L2
MGI:1351648
41 phenotypes from 3 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Magel2em2(IMPC)H/Magel2em2(IMPC)H
C57BL/6NTac-Magel2em2(IMPC)H/H 		abnormal locomotor behavior J:211773
decreased circulating serum albumin level J:211773
decreased circulating total protein level J:211773
Magel2tm1.1Mus/Magel2+
B6.129S2-Magel2tm1.1Mus 		abnormal hypothalamus secretion J:166548
abnormal suckling behavior J:166548
absent gastric milk in neonates J:166548
decreased body weight J:166548
decreased circulating glucose level J:166548
normal nervous system phenotype J:166548
perinatal lethality, incomplete penetrance J:166548
Magel2tm1.1Mus/Magel2+
involves: 129S2/SvPas * C57BL/6J 		perinatal lethality, incomplete penetrance J:166548
Magel2tm1Stw/Magel2+
C57BL/6-Magel2tm1Stw 		abnormal corpus luteum morphology J:144836
abnormal proestrus J:144836
decreased circulating testosterone level J:144836
decreased litter size J:144836
delayed estrous cycle J:144836
delayed vaginal opening J:144836
early reproductive senescence J:144836
impaired olfaction J:144836
maternal imprinting J:144836
postnatal lethality, incomplete penetrance J:144836
prolonged estrous cycle J:144836
pup cannibalization J:144836
Magel2tm1Stw/Magel2tm1Stw
C57BL/6-Magel2tm1Stw 		abnormal circadian behavior J:125637
abnormal locomotor circadian rhythm J:125637
decreased compensatory feeding amount J:125637
decreased locomotor activity J:125637
normal growth/size/body region phenotype J:125637
maternal imprinting J:125637
postnatal lethality, incomplete penetrance J:125637
reduced male fertility J:125637
Magel2tm1Stw/Magel2tm1Stw
C57BL/6-Magel2tm1Stw/J 		abnormal autophagy J:233299
decreased grip strength J:233299
decreased lean body mass J:233299
decreased locomotor activity J:233299
decreased skeletal muscle fiber size J:233299
decreased skeletal muscle weight J:233299
decreased vertical activity J:233299
increased body fat mass J:233299
increased skeletal muscle fiber size J:233299
obese J:233299
prenatal lethality, incomplete penetrance J:233299
normal respiratory system phenotype J:233299
scoliosis J:233299
skeletal muscle atrophy J:233299
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory