Yme1l1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Yme1l1
YME1-like 1 (S. cerevisiae)
MGI:1351651

21 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Yme1l1^tm1.1Tlan/Yme1l1^tm1.1Tlan involves: C57BL/6 * C57BL/6NCrl	embryonic lethality during organogenesis, complete penetrance	J:229455
Yme1l1^tm1Tlan/Yme1l1^tm1Tlan Tg(Ckmm-cre)5Khn/0 involves: C57BL/6 * C57BL/6NCrl * FVB	normal cardiovascular system phenotype	J:229455
	decreased circulating insulin level	J:229455
	impaired glucose tolerance	J:229455
	normal mortality/aging	J:229455
Yme1l1^tm1Tlan/Yme1l1^tm1Tlan Tg(Myh6-cre)2182Mds/0 involves: C57BL/6 * C57BL/6NCrl * FVB/N	abnormal cardiovascular system physiology	J:229455
	abnormal heart morphology	J:229455
	abnormal mitochondrial physiology	J:229455
	abnormal muscle physiology	J:229455
	abnormal myocardial fiber mitochondrial morphology	J:229455
	cardiac fibrosis	J:229455
	cardiac muscle necrosis	J:229455
	congestive heart failure	J:229455
	decreased heart left ventricle muscle contractility	J:229455
	decreased mitochondrial size	J:229455
	dilated cardiomyopathy	J:229455
	dilated heart left ventricle	J:229455
	increased cardiac muscle cell glucose uptake	J:229455
	increased circulating troponin T level	J:229455
	premature death	J:229455
	weight loss	J:229455

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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