Nr2f1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nr2f1
nuclear receptor subfamily 2, group F, member 1
MGI:1352451

16 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Mctp1^dwnd/Nr2f1^{tm1.1(KOMP)Mbp} involves: C57BL/6J * C57BL/6NJ * C57BL/10SnJ	abnormal cochlear hair cell morphology	J:264553
	abnormal cochlear inner hair cell morphology	J:264553
	abnormal cochlear outer hair cell morphology	J:264553
	abnormal utricular macula morphology	J:264553
	abnormal vestibular saccular macula morphology	J:264553
	fused vestibular saccule and utricle	J:264553
	impaired hearing	J:264553
	increased or absent threshold for auditory brainstem response	J:264553
	short scala media	J:264553
Nr2f1^tm2.1Mjts/Nr2f1⁺ Nr2f2^tm2.1Tsa/Nr2f2^tm2.1Tsa Tg(rx3-icre)1Mjam/0 involves: 129S7/SvEvBrd	abnormal optic fissure closure	J:157924
	coloboma	J:157924
Nr2f1^tm2.1Mjts/Nr2f1^tm2.1Mjts Nr2f2^tm2.1Tsa/Nr2f2⁺ Tg(rx3-icre)1Mjam/0 involves: 129S7/SvEvBrd	abnormal optic fissure closure	J:157924
	coloboma	J:157924
Nr2f1^tm2.1Mjts/Nr2f1^tm2.1Mjts Nr2f2^tm2.1Tsa/Nr2f2^tm2.1Tsa Tg(rx3-icre)1Mjam/0 involves: 129S7/SvEvBrd	abnormal eye development	J:157924
	abnormal optic stalk morphology	J:157924
	abnormal retina pigment epithelium morphology	J:157924
	absent optic disk	J:157924
	coloboma	J:157924
	microphthalmia	J:157924

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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