Nr4a1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nr4a1
nuclear receptor subfamily 4, group A, member 1
MGI:1352454

25 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Cd79a^tm1(cre)Reth/Cd79a⁺ Nr4a1^tm1Pcn/Nr4a1^tm1Pcn Nr4a3^em1Juz/Nr4a3^em1Juz involves: 129 * BALB/c * C57BL/6	decreased B cell apoptosis	J:306652
	normal immune system phenotype	J:306652
	increased B cell proliferation	J:306652
Ifi27^tm1Npm/Ifi27^tm1Npm Nr4a1^tm1Jmi/Nr4a1^tm1Jmi involves: 129 * C57BL/6 * Swiss Webster	normal cardiovascular system phenotype	J:212520
Nr4a1^tm1Jmi/Nr4a1^tm1Jmi Nr4a3^tm1Omc/Nr4a3^tm1Omc involves: 129S/SvEv * 129S2/SvPas * C57BL/6	abnormal bone marrow cell number	J:121903
	abnormal common myeloid progenitor cell morphology	J:121903
	abnormal leukopoiesis	J:121903
	abnormal myelopoiesis	J:121903
	abnormal spleen morphology	J:121903
	abnormal thymus morphology	J:121903
	anemia	J:121903
	decreased body size	J:121903
	decreased lymphocyte cell number	J:121903
	enlarged liver	J:121903
	enlarged lymph nodes	J:121903
	enlarged spleen	J:121903
	hunched posture	J:121903
	increased eosinophil cell number	J:121903
	increased granulocyte number	J:121903
	increased hematopoietic stem cell number	J:121903
	increased leukemia incidence	J:121903
	increased leukocyte cell number	J:121903
	increased neutrophil cell number	J:121903
	postnatal lethality, complete penetrance	J:121903
	ruffled hair	J:121903

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24