Nr4a3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nr4a3
nuclear receptor subfamily 4, group A, member 3
MGI:1352457

22 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nr4a3^tm1Omc/Nr4a3^tm1Omc involves: 129S/SvEv * C57BL/6	abnormal axon extension	J:93320
	abnormal axon guidance	J:93320
	abnormal endolymphatic duct morphology	J:73971
	abnormal hippocampus development	J:93320
	abnormal hippocampus pyramidal cell layer	J:93320
	abnormal semicircular canal morphology	J:73971
	abnormal sulcus ampullaris morphology	J:73971
	abnormal vestibular system physiology	J:73971
	bidirectional circling	J:73971
	decreased hippocampus pyramidal cell number	J:93320
	hyperactivity	J:73971
	impaired balance	J:73971
	increased neuron apoptosis	J:93320
	increased susceptibility to pharmacologically induced seizures	J:93320
	loss of hippocampal neurons	J:93320
	tonic-clonic seizures	J:93320
Nr4a3^tm1Wnt/Nr4a3⁺ involves: 129S4/SvJae	abnormal embryonic tissue morphology	J:89944
	embryonic growth retardation	J:89944
	prenatal lethality, incomplete penetrance	J:89944
Nr4a3^tm1Wnt/Nr4a3^tm1Wnt involves: 129S4/SvJae	abnormal embryonic tissue morphology	J:89944
	abnormal gastrulation	J:89944
	abnormal gastrulation movements	J:89944
	embryonic lethality between somite formation and embryo turning, complete penetrance	J:89944

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24