Nr4a3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nr4a3
nuclear receptor subfamily 4, group A, member 3
MGI:1352457

22 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nr4a3^tm1Omc/Nr4a3^tm1Omc involves: 129S/SvEv * C57BL/6	abnormal axon extension	J:93320
	abnormal axon guidance	J:93320
	abnormal endolymphatic duct morphology	J:73971
	abnormal hippocampus development	J:93320
	abnormal hippocampus pyramidal cell layer	J:93320
	abnormal semicircular canal morphology	J:73971
	abnormal sulcus ampullaris morphology	J:73971
	abnormal vestibular system physiology	J:73971
	bidirectional circling	J:73971
	decreased hippocampus pyramidal cell number	J:93320
	hyperactivity	J:73971
	impaired balance	J:73971
	increased neuron apoptosis	J:93320
	increased susceptibility to pharmacologically induced seizures	J:93320
	loss of hippocampal neurons	J:93320
	tonic-clonic seizures	J:93320
Nr4a3^tm1Wnt/Nr4a3⁺ involves: 129S4/SvJae	abnormal embryonic tissue morphology	J:89944
	embryonic growth retardation	J:89944
	prenatal lethality, incomplete penetrance	J:89944
Nr4a3^tm1Wnt/Nr4a3^tm1Wnt involves: 129S4/SvJae	abnormal embryonic tissue morphology	J:89944
	abnormal gastrulation	J:89944
	abnormal gastrulation movements	J:89944
	embryonic lethality between somite formation and embryo turning, complete penetrance	J:89944

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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