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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Nr6a1
nuclear receptor subfamily 6, group A, member 1
MGI:1352459
62 phenotypes from 7 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Nr6a1Gt(RRA042)Byg/Nr6a1Gt(RRA042)Byg
involves: 129P2/OlaHsd * C57BL/6 		abnormal embryo development J:149711
embryonic lethality, complete penetrance J:149711
Nr6a1tm1b(EUCOMM)Wtsi/Nr6a1tm1b(EUCOMM)Wtsi
C57BL/6N-Nr6a1tm1b(EUCOMM)Wtsi/Bay 		abnormal allantois morphology J:211773
abnormal chorioallantoic fusion J:211773
abnormal embryo development J:211773
abnormal embryo size J:211773
abnormal embryo turning J:211773
abnormal forebrain development J:211773
abnormal heart looping J:211773
abnormal heart morphology J:211773
abnormal hindbrain development J:211773
abnormal midbrain development J:211773
abnormal neural tube closure J:211773
abnormal neural tube morphology J:211773
abnormal optic vesicle formation J:211773
abnormal pericardium morphology J:211773
abnormal pharyngeal arch morphology J:211773
abnormal somite shape J:211773
abnormal tail bud morphology J:211773
abnormal visceral yolk sac morphology J:211773
embryonic growth retardation J:211773
embryonic lethality prior to tooth bud stage J:211773
pale yolk sac J:211773
preweaning lethality, complete penetrance J:211773
Nr6a1tm1c(EUCOMM)Wtsi/Nr6a1tm1c(EUCOMM)Wtsi
Ndor1Tg(UBC-cre/ERT2)1Ejb/0
involves: 129S/SvEv * C57BL/6 * C57BL/6N * SJL 		normal reproductive system phenotype J:204241
Nr6a1tm1Coo/Nr6a1tm1Coo
involves: 129S7/SvEvBrd * C57BL/6 		abnormal allantois morphology J:67377
abnormal brain development J:108393
abnormal caudal neuropore morphology J:67377
abnormal chorion morphology J:67377
abnormal cranial nerve morphology J:108393
abnormal developmental patterning J:67377
abnormal embryo development J:67377
abnormal embryonic tissue morphology J:67377
abnormal extraembryonic tissue morphology J:67377
abnormal hindgut morphology J:67377
abnormal neural tube closure J:67377
abnormal oculomotor nerve morphology J:108393
abnormal primitive streak morphology J:67377
abnormal spine curvature J:67377
abnormal trochlear nerve morphology J:108393
abnormal ventral body wall morphology J:67377
caudal body truncation J:67377
distended pericardium J:67377
embryonic lethality during organogenesis, complete penetrance J:67377
enlarged allantois J:67377
failure of chorioallantoic fusion J:67377
failure of initiation of embryo turning J:67377
incomplete somite formation J:67377
Nr6a1tm1d(EUCOMM)Wtsi/Nr6a1tm1d(EUCOMM)Wtsi
involves: 129S/SvEv * C57BL/6 * C57BL/6N * SJL 		abnormal embryo development J:204241
decreased embryo size J:204241
embryonic lethality, complete penetrance J:204241
impaired somite development J:204241
incomplete embryo turning J:204241
Nr6a1tm2Coo/Nr6a1tm2Coo
involves: 129S7/SvEvBrd * C57BL/6 		abnormal allantois morphology J:80978
abnormal chorion morphology J:80978
abnormal developmental patterning J:80978
abnormal extraembryonic tissue morphology J:80978
abnormal primitive streak morphology J:80978
abnormal tail bud morphology J:80978
absent hindgut J:80978
distended pericardium J:80978
embryonic lethality between somite formation and embryo turning, complete penetrance J:80978
enlarged allantois J:80978
failure of chorioallantoic fusion J:80978
failure of initiation of embryo turning J:80978
incomplete rostral neuropore closure J:80978
incomplete somite formation J:80978
Nr6a1tm3Coo/Nr6a1tm3Coo
Tg(Zp3-cre)93Knw/0
involves: 129S7/SvEvBrd * C57BL/6 		abnormal diestrus J:85054
abnormal oocyte morphology J:85054
decreased circulating estradiol level J:85054
decreased circulating follicle stimulating hormone level J:85054
decreased circulating progesterone level J:85054
decreased circulating testosterone level J:85054
decreased litter size J:85054
normal homeostasis/metabolism phenotype J:85054
polyovular ovarian follicle J:85054
prolonged diestrus J:85054
prolonged estrous cycle J:85054
reduced female fertility J:85054
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory